Modern agriculture faces unprecedented challenges: increasing global temperatures, water scarcity, less arable land to ...
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Considerations for RT-qPCR in molecular point of care testing devices
The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests becoming commonplace in schools, places of work and people’s homes. Antigen POCT has been pivotal in SARS-CoV-2 detection, particularly where reverse transcription PCR (RT-PCR) cannot be delivered in a timely manner. However, the use of antigen tests isn’t always appropriate due to variable sensitivity. RT-PCR – or RT-qPCR if using real-time detection – offers greater sensitivity and specificity. Leveraging this technology in POCT brings lab quality results to the point of need, providing rapid, accurate and actionable results to clinicians.
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New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
Let the application be your guide when deciding between LNA, MGB and BHQplus The many different chemistries available ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, qPCR
Since 13 May 2022, reports of monkeypox cases began to appear globally in regions not endemic to the monkeypox virus.1 ...
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Topics: Molecular Diagnostics, Disease detection
This is the second blog in a two-part series exploring solutions for infectious diseases in aquaculture. In the first ...
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Topics: Agrigenomics, PCR-based genotyping, NGS-based genotyping
Since early 2020, diagnostic laboratories have had to manage patient sample quantities being in a state of flux. Demand ...
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Topics: SARS-CoV-2, Nucleic acid extraction, Disease detection
This is the first blog in a two-part series exploring solutions for infectious diseases in aquaculture. This blog post ...
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Topics: Agrigenomics, Genomics
What’s changed for clinical labs as we enter the third year of COVID-19 testing? COVID-19, the illness caused by ...
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Topics: SARS-CoV-2
While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient ...
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Topics: Molecular Diagnostics, qPCR
This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop that is used widely in food, ...
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Topics: Agrigenomics, qPCR, PCR-based genotyping
The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests ...
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Topics: Molecular Diagnostics, qPCR
This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
But measurement science could help steer us in a better, more informed direction COVID-19 tests can indicate the ...
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Topics: qPCR, SARS-CoV-2
More innovative applications for Black Hole Quencher (BHQ) dyes In imaging and detection assay development, innovative ...
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Rice is the primary staple for more than half the world's population.1 With so many people relying on the crop for ...
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Topics: Agrigenomics, qPCR, PCR-based genotyping
What’s changed for clinical labs as we enter the third year of COVID-19 testing? COVID-19, the illness caused by ...
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Topics: SARS-CoV-2
What’s changed for clinical labs as we enter the third year of COVID-19 testing? COVID-19, the illness caused by ...
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Topics: SARS-CoV-2
The emergence of the Omicron lineage has quickly escalated to be a variant of concern by the World Health Organization ...
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Topics: Molecular Diagnostics, SARS-CoV-2
What’s changed for clinical labs as we enter the third year of COVID-19 testing?
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Topics: SARS-CoV-2
This is the final blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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On 22 November 2021, The Network for Genomics Surveillance in South Africa detected a new SARS-CoV-2 variant, named the ...
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Topics: Molecular Diagnostics, SARS-CoV-2
The decisions made by molecular breeding programmes have a substantial impact on the world around us, from productivity ...
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Topics: Agrigenomics, Next Generation Sequencing (NGS), NGS-based genotyping
We're excited to announce that the proposal to extend certain key provisions of the In Vitro Diagnostic Regulation ...
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Topics: Molecular Diagnostics
A fourth wave of COVID-19 has already emerged in many countries and a newly classified variant of concern, Omicron ...
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Topics: Molecular Diagnostics, SARS-CoV-2, Disease detection
Many cultivated crops with agronomic significance, including wheat, peanut, oat, banana, potato, coffee and strawberry, ...
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Topics: Agrigenomics, NGS-based genotyping
This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications
This is the second blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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SARS-CoV-2 mutations and associated new variants are being reported regularly in the media and scientific literature. ...
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Topics: Molecular Diagnostics, SARS-CoV-2
In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges ...
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Topics: Molecular Diagnostics, qPCR, SARS-CoV-2
A shortcut to understanding how to prepare for IVDR In today’s global environment, even small regulatory changes in one ...
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Topics: Molecular Diagnostics
This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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Aquaculture breeding programmes adopt genomic technologies, including genotyping, to increase genetic gain for specific ...
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Topics: Agrigenomics, PCR-based genotyping, Nucleic acid extraction
The COVID-19 pandemic brought tremendous change to the molecular diagnostics (MDx) industry, delivering opportunities ...
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Topics: Molecular Diagnostics, SARS-CoV-2
As SARS-CoV-2 variants continue to threaten public health, officials are looking beyond clinical tests to track ...
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Topics: SARS-CoV-2
Emerging SARS-CoV-2 variants of concern and variants of interest are defined by agencies such as the World Health ...
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Topics: SARS-CoV-2
Informed plant breeding decisions help drive the field of agrigenomics towards ever-increasing agricultural ...
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Topics: Agrigenomics, Next Generation Sequencing (NGS), Nucleic acid extraction
A common mistake when initiating an agrigenomics project is failing to consider specific sample composition before ...
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Topics: Agrigenomics, Nucleic acid extraction
The global demand for fish and fish products continues to increase as consumers focus on health-conscious ways to add ...
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Topics: Agrigenomics, Genomics
As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible ...
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Topics: Molecular Diagnostics, SARS-CoV-2
In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted ...
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Topics: Agrigenomics, Genomics, NGS-based genotyping
Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
“In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish ...
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Topics: Genomics, PCR-based genotyping
Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping
Following up with the panelists from our recent COVID-19 webinar, Part 3 of 3 In the previous two blog posts in this ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
Following up with the panelists from our recent COVID-19 webinar, Part 2 of 3 In the face of a rapidly evolving ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3 The COVID-19 pandemic has presented ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal” ...
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Topics: Molecular Diagnostics, Genomics, qPCR, SARS-CoV-2
Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping
It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned to ...
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Topics: Molecular Diagnostics, Genomics, qPCR, SARS-CoV-2
We’re not rejecting you, just your oligo PCR is arguably one of the most enabling technologies of modern molecular ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
LGC, Biosearch Technologies is excited to announce the expansion of SeqSNP targeted genotyping by sequencing (GBS) ...
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Topics: Agrigenomics, Genomics, NGS-based genotyping
On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they will ...
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Topics: Molecular Diagnostics, SARS-CoV-2
Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and ...
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Topics: Genomics, Next Generation Sequencing (NGS), NGS-based genotyping
In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
*Since the original publication of this blog, LGC, Biosearch Technologies is now the only acceptable commercial ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
Coronavirus, or COVID-19, is an infectious virus that is spreading rapidly around the world and the World Health ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2
The development of new genomic sequencing techniques and bioinformatics analysis in the last decade has led to massive ...
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Topics: Molecular Diagnostics, Genomics, PCR-based genotyping, Next Generation Sequencing (NGS)
Best practice in sample collection for SeqSNP targeted genotyping by sequencing projects When good goes in, great comes ...
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Topics: Genomics, PCR-based genotyping, NGS-based genotyping
Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the ...
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Topics: Agrigenomics, Genomics, Next Generation Sequencing (NGS), NGS-based genotyping
“Experience of artificial fertilisation, such as is effected with ornamental plants in order to obtain new variations ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping, Next Generation Sequencing (NGS), NGS-based genotyping
Blindness, cardiovascular disease, and stroke are all long-term health problems that can be caused by type 1 diabetes ...
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Topics: Genomics, PCR-based genotyping, Disease detection
Plant and animal breeding programmes often take generations to improve quality and yield but using a genotyping ...
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Topics: Agrigenomics, Genomics, Next Generation Sequencing (NGS), NGS-based genotyping
Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays
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Topics: Genomics, NGS-based genotyping
Food security is a major global threat and traditional methods of plant and animal breeding will not be sufficient to ...
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Topics: Agrigenomics, Next Generation Sequencing (NGS), NGS-based genotyping
Diversity is the spice of life and is also key to breeding rice that delivers increased yields. Rice is a crucial ...
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Topics: PCR-based genotyping
Imagine a time capsule the size of a shoebox that holds all the information currently on the internet that can be ...
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Topics: Genomics, Nucleic acid extraction
Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice ...
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To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data ...
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Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous ...
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With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the ...
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Topics: Agrigenomics, Genomics, NGS-based genotyping
Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global population, ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping
Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5 ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping
3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious and ...
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Topics: Genomics, PCR-based genotyping, Disease detection
Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our ...
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LGC's Genomics Division has signed a memorandum of understanding (MOU) with Chinese health management expert Personal ...
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A recent study coordinated by LGC and published in the journal Analytical Chemistry, has demonstrated the potential of ...
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Topics: Real-time PCR
New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus ...
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Topics: RNA FISH, Disease detection
It’s time to forget what you know about heating your PCR plates for end-point PCR. Water is the way to go. Where ...
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Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand ...
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Topics: Genomics, PCR-based genotyping
Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable the ...
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Topics: Agrigenomics, Genomics, PCR-based genotyping, NGS-based genotyping
Screen more markers faster and bring crops with superior traits to the market quicker.
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Topics: PCR-based genotyping
It seems everyone wants to do more with less, and automate the process as well. But this can cause a number of ...
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It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a ...
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As the Zika virus outbreak spreads, a wave of international concern has grown, and scientists have scrambled to ...
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Topics: Real-time PCR
We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide modification: the Thio C6 ...
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Modern breeding methods rely on the identification and utilization of molecular markers associated with traits ...
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Topics: Agrigenomics
For DNA Technology’s existing customers, don’t fret! The online ordering process will remain the same, as will the team ...
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OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...
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Topics: Molecular Diagnostics, Real-time PCR, Oligo synthesis and modifications
LGC Biosearch Technologies has developed a new qPCR probe format powered by Black Hole Quencher® technology known as ...
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Topics: Real-time PCR
At this year’s 24th annual Plant & Animal Genome (PAG) conference, LGC Biosearch Technologies hosted a symposium ...
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LGC Biosearch Technologies is announcing the upcoming release of a new qPCR probe format known as BHQnova™ probes. This ...
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Topics: Real-time PCR
This week, we continue our Know Your Oligo Mod series and we will focus on a very basic, yet extremely versatile ...
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Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine, ...
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In this installment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary quencher chromophores ...
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Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...
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Topics: Real-time PCR, RNA FISH
Since its inception, qPCR has been recognized as a powerful molecular method. However, the application of this ...
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Topics: Real-time PCR
In the setup of a qPCR experiment, one of the first decisions to make is which detection method to use. This generally ...
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Topics: Real-time PCR
This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...
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In a recent webinar, Dr. James Willey describes a two color fluorometric assay for more robust quantitation of nucleic ...
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Topics: Real-time PCR
Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in forensics, ...
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Topics: Real-time PCR, PCR-based genotyping
The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...
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Biosearch Technologies has launched qPCRdesign.com, a new microsite targeted specifically for your quantitative PCR ...
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Topics: Real-time PCR
Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...
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The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This ...
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Topics: Molecular Diagnostics, Real-time PCR
Don’t waste time performing an extra step. Cut back on pipetting and order a ValuMix™ Assay to have your probes and ...
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Topics: Real-time PCR
Do you remember when the most popular method of DNA amplification involved multiple hybridizations, followed by single ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...
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Topics: Real-time PCR, RNA FISH
Biosearch Technologies, Inc. (Biosearch) announced today that the company has implemented a rapid response to the ...
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Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated, custom-manufactured oligonucleotides and ...
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Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently ...
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Topics: Molecular Diagnostics, Real-time PCR
A "Referral from the Doctor" Blog Article- In qPCR, fluorescent modified oligos may be either linear or non-linear in ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- The mathematical model of PCR is based on the assumption that each DNA ...
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A "Referral from the Doctor" Blog Article- Fluorescent probes are used in biochemical assays to monitor specific events ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Quantitative real-time PCR (qPCR) was developed as a means to detect the ...
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Topics: Real-time PCR
If you run quantitative real-time PCR (qPCR) assays, the chances are that you’ve seen some strange looking ...
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Topics: Real-time PCR
I’ve always wondered why scientists have earned themselves this infamous reputation of dressing poorly and ...
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A "Referral from the Doctor" Blog Article- ROX in qPCR Quantitative real-time RT-PCR was developed as a means of ...
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Topics: Real-time PCR
Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...
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Topics: Real-time PCR
Biosearch Technologies is proud to sponsor the first IVD Technology Virtual Conference and Tradeshow. This free online ...
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Topics: Molecular Diagnostics
Biosearch Technologies today announces that it has entered into a new license relationship with QIAGEN (NASDAQ: QIA, ...
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Topics: Real-time PCR
When the polymerase chain reaction (PCR) was first described, the Klenow fragment of Escherichia coli DNA Polymerase I ...
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Topics: Real-time PCR, qPCR
It can be difficult to transition a product from research to commercialization. It’s simply not feasible to conduct ...
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Topics: Molecular Diagnostics
A "Referral from the Doctor" Blog Article- Research trends in laboratories today increasingly steer towards gene ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Scorpions®Primers are dual-labeled FRET probes that combine a Molecular ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Molecular Beacons are a special type of dual-labeled oligonucleotide probe. ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- A BHQ® probe is a dual-labeled oligonucleotide covalently labeled with a ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- The aim of the Polymerase Chain Reaction (PCR) method is to amplify or ...
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Topics: Real-time PCR
At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS laboratories (ETS) scientist Rich DeScenzo ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Genomic DNA contamination has been a hot topic for qPCR researchers since ...
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Topics: Real-time PCR
By now, you've no doubt read about the reductions in error, cost and time that can be achieved by multiplexing ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- ε = m.c.2 (shall I explain? slope efficiency equals manageable and ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Competitive qRT-PCR has become a lost art. Early titans of probe-based PCR ...
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Topics: Real-time PCR
A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...
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A "Referral from the Doctor" Blog Article- Top 10 Reference Genes for probe-based Real-time PCR in 2009: • Acidic ...
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Topics: Real-time PCR
When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR. When the ...
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Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...
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