The BiosearchTech Blog

When you don’t need an EUA for SARS-CoV-2 testing

On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they will be holding to answer technical questions about developing, validating, and implementing…

The BiosearchTech Blog

How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

Posted on Tue, May 04, 2021 @ 09:03 AM

Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible ...

Topics: Molecular Diagnostics, Coronavirus, MDx, SARS-CoV-2, Variants

Best practices for implementing targeted genotyping by sequencing

Posted on Wed, Dec 02, 2020 @ 08:53 AM

In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted ...

Topics: Genomics, AgBio, Genomic Selection, Marker Assisted Selection, Targeted Genotyping, Targeted Genotyping by Sequencing

Building resilience into SARS-CoV-2 testing workflows: considerations for choosing an RNA isolation method

Posted on Wed, Oct 21, 2020 @ 09:00 AM

As we start to close in on a full year of the COVID-19 pandemic, molecular diagnostics labs are still facing supply ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

How high-throughput genotyping automation and KASP marker libraries connect research labs with commercial breeders to accelerate crop improvement

Posted on Wed, Oct 07, 2020 @ 09:31 AM

“In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish ...

Topics: Genomics, Genotyping, KASP

Employee spotlight: Meet Darshna "Dusty" Vyas

Posted on Mon, Sep 14, 2020 @ 08:15 AM

Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her ...

Topics: Agrigenomics, Genomics, KASP

Pressing COVID-19 testing issues of today and the near future

Posted on Wed, Aug 26, 2020 @ 07:57 AM

Following up with the panelists from our recent COVID-19 webinar, Part 3 of 3 In the previous two blog posts in this ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

Sensitivity and accuracy in COVID-19 testing

Posted on Wed, Aug 19, 2020 @ 07:56 AM

Following up with the panelists from our recent COVID-19 webinar, Part 2 of 3 In the face of a rapidly evolving ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

Scaling up COVID-19 viral testing

Posted on Wed, Aug 12, 2020 @ 07:47 AM

Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3 The COVID-19 pandemic has presented ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

Enabling a rapid response to COVID-19 by Honeywell and LGC, Biosearch Technologies

Posted on Wed, Jul 29, 2020 @ 12:40 PM

As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal” ...

Topics: Molecular Diagnostics, Genomics, qPCR, Coronavirus

Establishment of KASP marker library for genetic diversity analysis in Brassica rapa crops

Posted on Tue, Jul 14, 2020 @ 08:17 AM

Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique ...

Topics: Agrigenomics, Genomics, KASP

Robust supply chains and open testing systems: How our AgBio roots meet the FDA's EUA process to enable solutions to the COVID-19 pandemic

Posted on Tue, May 19, 2020 @ 08:18 AM

It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned to ...

Topics: Molecular Diagnostics, Genomics, qPCR, Coronavirus

Behind the scenes: How our oligo synthesis team contributes to the reliability of your assays

Posted on Thu, Apr 30, 2020 @ 02:13 PM

We’re not rejecting you, just your oligo PCR is arguably one of the most enabling technologies of modern molecular ...

Topics: Molecular Diagnostics, Genomics, Coronavirus, Oligo synthesis

Expanded SeqSNP support with new NGS lab in Middleton, WI

Posted on Tue, Apr 14, 2020 @ 09:15 AM

LGC, Biosearch Technologies is excited to announce the expansion of SeqSNP targeted genotyping by sequencing (GBS) ...

Topics: Agrigenomics, Genomics, GBS, SeqSNP, Genotyping by Sequencing (GBS), Targeted Genotyping by Sequencing

When you don’t need an EUA for SARS-CoV-2 testing

Posted on Fri, Apr 10, 2020 @ 03:00 PM

On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they will ...

Topics: Molecular Diagnostics, Coronavirus

New NGS service lab now open in Middleton, WI for expanded global support

Posted on Wed, Apr 01, 2020 @ 09:27 AM

Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and ...

Topics: Genomics, Targeted Genotyping, Next Generation Sequencing (NGS)

Addressing COVID-19 together: LGC, Biosearch Technologies and Shanghai Liferiver Biotechnology Co., Ltd.

Posted on Tue, Mar 31, 2020 @ 10:13 AM

In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...

Topics: Molecular Diagnostics, Custom Oligos, Genomics, Coronavirus

What diagnostic test makers and CLIA labs in the US need to know about Emergency Use Authorization (EUA)

Posted on Tue, Mar 24, 2020 @ 11:58 AM

*Since the original publication of this blog, LGC, Biosearch Technologies is now the only acceptable commercial ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

Coronavirus outbreak: Collaboration to meet the challenge

Posted on Mon, Mar 16, 2020 @ 12:30 PM

Coronavirus, or COVID-19, is an infectious virus that is spreading rapidly around the world and the World Health ...

Topics: Molecular Diagnostics, Genomics, Coronavirus

Molecular diagnostics: how can NGS live up to its promises?

Posted on Wed, Jan 29, 2020 @ 09:37 AM

The development of new genomic sequencing techniques and bioinformatics analysis in the last decade has led to massive ...

Topics: Molecular Diagnostics, Genomics, Genotyping, Next Generation Sequencing (NGS)

Back to basics - the crucial step of sample collection

Posted on Wed, Jan 15, 2020 @ 09:37 AM

Best practice in sample collection for SeqSNP targeted genotyping by sequencing projects When good goes in, great comes ...

Topics: Genomics, Genotyping, Sequencing, SeqSNP

Genomic selection: can it accelerate livestock breeding?

Posted on Wed, May 01, 2019 @ 08:44 AM

Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the ...

Topics: Agrigenomics, Genomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Arrays, Genomic Library, Targeted Genotyping by Sequencing

The women of LGC, Biosearch Technologies

Posted on Fri, Mar 29, 2019 @ 09:24 AM

We've heard it said for years, "TV will rot your brain". But in the case of our three colleagues below, that ...

Topics: Genomics

Agrigenomics: how can NGS contribute to global food security?

Posted on Wed, Mar 06, 2019 @ 08:33 AM

“Experience of artificial fertilisation, such as is effected with ornamental plants in order to obtain new variations ...

Topics: Agrigenomics, Genomics, Sequencing, KASP, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Crop Breeding

A way to prevent type 1 diabetes?

Posted on Wed, Feb 13, 2019 @ 08:08 AM

Blindness, cardiovascular disease, and stroke are all long-term health problems that can be caused by type 1 diabetes ...

Topics: Genomics, Genotyping, Diabetes

How targeted GBS-driven genomic selection can help you get to market faster

Posted on Wed, Jan 16, 2019 @ 11:22 AM

Plant and animal breeding programs often take generations to improve quality and yield but using a genotyping protocol ...

Topics: Genomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Animal Breeding, Genomic Library

Genomic selection: methods in crop and animal breeding

Posted on Wed, Jan 09, 2019 @ 08:48 AM

Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays

Topics: Genomics, Sequencing, Targeted Genotyping

Our hungry planet: new tools in agrigenomics are key to food security

Posted on Tue, Dec 11, 2018 @ 08:32 AM

Food security is a major global threat and traditional methods of plant and animal breeding will not be sufficient to ...

Topics: Agrigenomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Arrays

Accelerating rice improvement in South Asia

Posted on Thu, Jul 26, 2018 @ 09:26 AM

Diversity is the spice of life and is also key to breeding rice that delivers increased yields. Rice is a crucial ...

Topics: KASP

Revolutionising cancer treatment one Array at a time

Posted on Tue, Jul 10, 2018 @ 09:05 AM

While the science of pharmacogenomics has been around for years, its popularity is starting to pick up steam as ...

Topics: Genomics, IntelliQube, Pharmacogenomics

Pack it up, pack it in, let me begin: A look at the future of DNA data storage

Posted on Thu, Jun 28, 2018 @ 09:13 AM

Imagine a time capsule the size of a shoebox that holds all the information currently on the internet that can be ...

Topics: Genomics, DNA

Warning! Pitfalls ahead: How to avoid the most common Stellaris RNA FISH mistakes

Posted on Tue, May 29, 2018 @ 08:32 AM

Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice ...

Topics: Genomics, Stellaris

Seven of the hottest topics at PAG 2018

Posted on Tue, May 08, 2018 @ 08:00 AM

Visiting PAG is exhilarating, energising and somewhat overwhelming. With over 3000 leading plant and animal genetics ...

Topics: Genomics, AgBio, Genotyping, CRISPR

Shining a light on gene expression and regulation one cell at a time

Posted on Thu, Apr 19, 2018 @ 10:51 AM

To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data ...

Topics: RNA FISH, Genomics, Stellaris

The Women of LGC

Posted on Thu, Mar 29, 2018 @ 08:45 AM

Ask any little girl what they want to be when they grow up and you may hear things like, princess, ballerina, pop star, ...

Topics: Genomics

In case you missed it: Stellaris RNA FISH lunch-and-learn

Posted on Tue, Jan 16, 2018 @ 08:35 AM

Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous ...

Topics: Genomics, Stellaris

Tackling food crisis through cost effective, target enriched sequencing

Posted on Wed, Dec 13, 2017 @ 08:07 AM

With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the ...

Topics: Agrigenomics, Genomics, AgBio, Genomic Selection, SeqSNP, Marker Assisted Selection, MAS

New SNPs identified in the hunt for new genetic weapons targeting leaf rust in wheat

Posted on Tue, Nov 21, 2017 @ 09:25 AM

Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global population, ...

Topics: Agrigenomics, Genomics, KASP

Super-crops helping to feed Africa

Posted on Fri, Nov 03, 2017 @ 09:08 AM

Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5 ...

Topics: Agrigenomics, Genomics, KASP

How genotyping is aiding in the fight against malaria

Posted on Wed, Sep 20, 2017 @ 08:11 AM

3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious and ...

Topics: Genomics, IntelliQube, Genotyping, Malaria

Lunch & Learn: Stellaris RNA FISH

Posted on Thu, Jul 06, 2017 @ 08:07 AM

Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our ...

Topics: Genomics, Stellaris

Stem cell research and genomic initiatives highlighted at DNA Day celebration

Posted on Tue, May 09, 2017 @ 08:42 AM

International DNA day celebrates the successful completion of the Human Genome Project in 2003 and the discovery of ...

Topics: Genomics

It’s official! Personal Health becomes first China demonstration laboratory site for LGC’s Nexar System

Posted on Wed, May 03, 2017 @ 07:05 AM

LGC's Genomics Division has signed a memorandum of understanding (MOU) with Chinese health management expert Personal ...

Topics: Announcement, Genomics, High-Throughput

CROP Conference 2017

Posted on Thu, Apr 20, 2017 @ 08:10 AM

On 02 April 2017 Amsterdam hosted the annual CROP Conference which was attended by global senior industry officials and ...

Topics: AgBio

Digital PCR – improving reproducible molecular methods in the clinic

Posted on Thu, Apr 06, 2017 @ 08:40 AM

A recent study coordinated by LGC and published in the journal Analytical Chemistry, has demonstrated the potential of ...

Topics: Real-time PCR

Better, faster, cheaper: How automation is improving laboratory quality

Posted on Wed, Mar 22, 2017 @ 08:24 AM

"Put in your samples, put in your assays, hit the green button and go!" It seems simple because it really is that ...

Topics: IntelliQube, SLAS2017

Shining a light on how Zika virus may spread from mothers to human fetuses

Posted on Mon, Mar 06, 2017 @ 08:37 AM

New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus ...

Topics: Stellaris, Zika

Water – Back to Basics for Thermal Cycling

Posted on Tue, Feb 28, 2017 @ 08:13 AM

It’s time to forget what you know about heating your PCR plates for end-point PCR. Water is the way to go. Where ...

Topics: Thermal Cycler, Water Bath, Hydrocycler2

Overcoming drought-intolerance in maize to feed the growing Asian population

Posted on Wed, Feb 15, 2017 @ 07:53 AM

Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand ...

Topics: Genomics, Genotyping, KASP

Automate to Accelerate and Scale-up SNP-based Genotyping Workflows!

Posted on Thu, Feb 02, 2017 @ 07:14 AM

The advent of and ongoing improvements to next-generation sequencing technologies is driving the continuing and ...

Topics: Genomics, SLAS2017

Multiple Misunderstandings: Learning from Genetic Determinism

Posted on Mon, Jan 23, 2017 @ 08:12 AM

Nature versus nurture. It’s a tale as old as time. When Craig Venter made the comment after the human genome sequence ...

Topics: Genomics

Helping to Feed the World with Genotyping by Sequencing

Posted on Tue, Jan 17, 2017 @ 07:42 PM

Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable the ...

Topics: Genomics, Genotyping, Sequencing, GBS

Accelerating Trait Discovery at PAG

Posted on Thu, Jan 12, 2017 @ 08:15 AM

The 25th annual International Plant & Animal Genome (PAG) conference is right around the corner and LGC will be in San ...

Topics: Announcement

Faster, stronger, quicker: SSR to KASP will get you there

Posted on Mon, Jan 09, 2017 @ 07:05 AM

Screen more markers faster and bring crops with superior traits to the market quicker.

Topics: Genotyping

Multiplex your qPCR and Walk-away

Posted on Thu, Dec 15, 2016 @ 08:17 AM

It seems everyone wants to do more with less, and automate the process as well. But this can cause a number of ...

Topics: Genomics, Douglas Scientific, IntelliQube, qPCR

On Your Mark, Get Set, Map!

Posted on Mon, Dec 12, 2016 @ 08:10 AM

You wouldn’t just read the first chapter of a book and then stop. Nor would you go to the theatre and see one act of a ...

Topics: Genomics

A Stellar-is Year in the Making

Posted on Wed, Dec 07, 2016 @ 08:05 AM

It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a ...

Topics: Product Information, RNA FISH, Genomics, Stellaris

Molded for our Purpose

Posted on Mon, Dec 05, 2016 @ 07:30 AM

With the discovery of the double helix, we learned how genes are copied and how genetic information was passed on. From ...

Topics: Genomics

Buddy Up: The Double Helix

Posted on Mon, Nov 28, 2016 @ 07:15 AM

The secret of life. That’s what Francis Crick and James Watson claimed they had discovered back in Cambridge, England ...

Topics: Genomics

Genes, Proteins & DNA: Our Hereditary Software

Posted on Mon, Nov 21, 2016 @ 07:17 AM

In the early 1900s, scientists found that the function of genes was to make proteins, disproving the earlier idea that ...

Topics: Genomics

"X" Marks the Spot: A Closer Look at Chromosomes

Posted on Mon, Nov 14, 2016 @ 07:28 AM

The strands of DNA in your cells are organized into pieces called chromosomes. Chromosomes are further organized into ...

Topics: Genomics

The Art of Neuroscience

Posted on Tue, Oct 11, 2016 @ 12:17 PM

Neuroscientists are renowned for working across a number of fields spanning the life sciences and social sciences as ...

Topics: Genomics, Contest, Neuroscience

Excel Autocorrect Fails the Genomics Community - Are your Results Excellent or Excel-not?

Posted on Thu, Sep 08, 2016 @ 09:30 AM

Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne, Australia have blamed a default autocorrect ...

Topics: Genomics, Data, Research

qPCR-based Molecular Diagnostics at the Forefront of Zika Surveillance

Posted on Tue, Aug 23, 2016 @ 02:00 PM

As the Zika virus outbreak spreads, a wave of international concern has grown, and scientists have scrambled to ...

Topics: Real-time PCR

Know Your Oligo Mod: Thio C6 Linker

Posted on Thu, Jul 14, 2016 @ 02:00 PM

We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide modification: the Thio C6 ...

Topics: Oligo Modifications

A Complete Ecosystem to Accelerate Breeding Programs [Infographic]

Posted on Tue, Jun 28, 2016 @ 02:00 PM

Modern breeding methods rely on the identification and utilization of molecular markers associated with traits ...

Topics: Agrigenomics

DNA Technology is now LGC Biosearch Technologies

Posted on Tue, Jun 14, 2016 @ 03:52 PM

For DNA Technology’s existing customers, don’t fret! The online ordering process will remain the same, as will the team ...

Topics: Announcement

Photoblog: Behind the scenes of oligo synthesis

Posted on Wed, May 18, 2016 @ 03:00 PM

OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...

Topics: Molecular Diagnostics, Real-time PCR, Custom Oligos

Hey! Biosearchtech.com looks different

Posted on Thu, Apr 28, 2016 @ 03:15 PM

We are pleased to announce that LGC Biosearch Technologies’ released a new and improved biosearchtech.com. Thank you to ...

Topics: Announcement

Nova is the new black

Posted on Thu, Apr 14, 2016 @ 02:00 PM

LGC Biosearch Technologies has developed a new qPCR probe format powered by Black Hole Quencher® technology known as ...

Topics: Real-time PCR

Learn about the latest developments in technologies for molecular breeding programs

Posted on Thu, Mar 31, 2016 @ 02:00 PM

At this year’s 24th annual Plant & Animal Genome (PAG) conference, LGC Biosearch Technologies hosted a symposium titled ...

Topics: Announcement

Imaging Stellaris Assays Part III: Creating Professional, Publication-ready Images

Posted on Thu, Mar 10, 2016 @ 02:00 PM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone over ...

Topics: RNA FISH

Introducing BHQnova Probes for qPCR - Join the Early Access Program

Posted on Mon, Feb 29, 2016 @ 02:00 PM

LGC Biosearch Technologies is announcing the upcoming release of a new qPCR probe format known as BHQnova™ probes. This ...

Topics: Real-time PCR

Welcome to the Stellaris® Citation Center

Posted on Thu, Feb 11, 2016 @ 02:16 PM

We have recently released a Stellaris® RNA FISH Citation Center to make it easy to find publications related to your ...

Topics: RNA FISH

Designing Stellaris RNA FISH Probes Part I: Increasing Probe Count

Posted on Thu, Jan 14, 2016 @ 02:00 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells and ...

Topics: RNA FISH

Know Your Oligo Mod: 3' Spacer C3

Posted on Thu, Oct 15, 2015 @ 02:15 PM

This week, we continue our Know Your Oligo Mod series and we will focus on a very basic, yet extremely versatile ...

Topics: Real-time PCR, Oligo Modifications

Imaging Stellaris Assays Part II: How to Acquire Stunning Images

Posted on Thu, Sep 24, 2015 @ 02:30 PM

Here we continue our “Imaging Stellaris Assays” blog series. We last left off talking about the most important ...

Topics: RNA FISH

Runaway RNA Stays Put

Posted on Thu, Sep 17, 2015 @ 02:00 PM

The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the ...

Topics: RNA FISH

Imaging Stellaris Assays Part I: Get to Know Your Microscope

Posted on Thu, Aug 27, 2015 @ 05:00 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of ...

Topics: RNA FISH

The AGCT’s of DNA Synthesis

Posted on Tue, Aug 11, 2015 @ 02:00 PM

Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine, ...

Topics: Custom Oligos, Synthesis Reagents

Know Your Oligo Mod: BHQ® (Black Hole Quencher®) Dyes

Posted on Thu, Jul 23, 2015 @ 02:00 PM

In this installment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary quencher chromophores ...

Topics: Custom Oligos

Summer 2015 Promotion

Posted on Thu, Jul 09, 2015 @ 02:00 PM

The summer promotion is back! For the month of July, use your Biosearchtech.com account to place an order and take 5% ...

Topics: Announcement

And the Consensus (Sequence) is...

Posted on Thu, Jun 11, 2015 @ 02:31 PM

Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...

Topics: Real-time PCR, RNA FISH

Research Highlight: Bringing Vision Research into Focus

Posted on Thu, May 28, 2015 @ 02:14 PM

Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers ...

Topics: RNA FISH

MIQE Goes Digital with Open Access qPCR Guide

Posted on Thu, May 21, 2015 @ 02:00 PM

Since its inception, qPCR has been recognized as a powerful molecular method. However, the application of this ...

Topics: Real-time PCR

FISH-ing for Fusions: A unique approach to fusion gene mRNA & pre-mRNA detection in cancer

Posted on Fri, May 15, 2015 @ 01:00 PM

This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia, PA ...

Topics: RNA FISH

Molecular Methods Research Finds a New Home

Posted on Thu, Apr 30, 2015 @ 02:00 PM

The need for improved diligence in research reporting has been echoed in numerous publications which cast doubt on the ...

Topics: Real-time PCR

Celebrate World DNA Day 2015

Posted on Tue, Apr 21, 2015 @ 03:02 PM

This Saturday, April 25, 2015, will commemorate the 12th World DNA Day - A holiday which is not well known to most ...

Topics: Custom Oligos

How Much is Your qPCR Assay Really Costing You?

Posted on Thu, Apr 02, 2015 @ 02:00 PM

In the setup of a qPCR experiment, one of the first decisions to make is which detection method to use. This generally ...

Topics: Real-time PCR

Research Highlight: Localizing long non-coding RNA (lncRNA)

Posted on Thu, Mar 12, 2015 @ 02:00 PM

A recent paper published in Molecular Cell by Dimitrova et al. from the lab of Dr. Tyler Jacks at MIT, used Stellaris® ...

Topics: RNA FISH

The 4Cs of Stellaris® RNA FISH Buffers

Posted on Thu, Feb 26, 2015 @ 02:00 PM

Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its ...

Topics: RNA FISH

Know Your Oligo Mod: Phosphorothioate Bonds

Posted on Thu, Feb 12, 2015 @ 02:00 PM

This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...

Topics: Custom Oligos, Oligo Modifications

BHQplus Probes Optimize Multiplex Competitive qRT-PCR in Diagnostics

Posted on Thu, Jan 29, 2015 @ 02:00 PM

In a recent webinar, Dr. James Willey describes a two color fluorometric assay for more robust quantitation of nucleic ...

Topics: Real-time PCR

A Successful Duo for Accurate, Speedy, and Economical SNP Genotyping

Posted on Thu, Jan 08, 2015 @ 11:30 AM

Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in forensics, ...

Topics: Real-time PCR, Product Information, SNP Genotyping

Know Your Oligo Mod: Methylene Blue

Posted on Tue, Dec 09, 2014 @ 02:02 PM

The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...

Topics: Custom Oligos, Oligo Modifications

Unraveling the Neural Web: Stellaris® RNA FISH for Neuroscience Research

Posted on Thu, Nov 13, 2014 @ 03:45 PM

Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or mixed ...

Topics: RNA FISH, Lab Method

Five Ways Controls Can Demystify Your Stellaris® RNA FISH Experiment

Posted on Tue, Nov 04, 2014 @ 02:13 PM

Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time interrogating a sample with a new ...

Topics: RNA FISH, Lab Method

Check out our new website qPCR Design Lab @ qPCRdesign.com

Posted on Thu, Oct 23, 2014 @ 02:00 PM

Biosearch Technologies has launched qPCRdesign.com, a new microsite targeted specifically for your quantitative PCR ...

Topics: Real-time PCR, Design Services

Delivering Oligos by Nanomole Units

Posted on Wed, Oct 15, 2014 @ 11:00 AM

Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...

Topics: Real-time PCR, Custom Oligos

RT-qPCR Molecular Diagnostics Assist Workers at the Forefront of Ebola Outbreak.

Posted on Thu, Sep 25, 2014 @ 11:30 AM

The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This ...

Topics: Molecular Diagnostics, Real-time PCR, Biodefense

One Step too Many? Simplify your qPCR Protocol.

Posted on Thu, Feb 27, 2014 @ 10:02 AM

Don’t waste time performing an extra step. Cut back on pipetting and order a ValuMix™ Assay to have your probes and ...

Topics: Real-time PCR, Product Information

Upcoming Holiday Schedule

Posted on Fri, Dec 20, 2013 @ 01:09 PM

Biosearch will be observing these upcoming holidays and will be closing our US facilities on the following dates: ...

Topics: Announcement

Biosearch Technologies Executes Exclusive License for turboFISH™

Posted on Mon, Oct 07, 2013 @ 07:29 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Biosearch Technologies Acquires Majority Stake in LightSpeed Genomics

Posted on Wed, Sep 25, 2013 @ 07:25 AM

Biosearch has acquired a majority stake in LightSpeed Genomics, Inc. (LSG), a Santa Clara, California-based company ...

Topics: Announcement, RNA FISH

30 Years: The Impact of PCR

Posted on Thu, Sep 05, 2013 @ 09:29 AM

Do you remember when the most popular method of DNA amplification involved multiple hybridizations, followed by single ...

Topics: Real-time PCR

RT-qPCR and the Stellaris FISH Method

Posted on Fri, Apr 26, 2013 @ 10:32 AM

A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...

Topics: Real-time PCR, RNA FISH, Referral from the Doctor

Biosearch Technologies Launches New GMP Production Facility and Successfully Certifies to ISO 13485:2003

Posted on Thu, Apr 18, 2013 @ 08:00 AM

Biosearch Technologies, Inc. (Biosearch), a leader in the development and manufacture of GMP grade oligonucleotides, ...

Topics: Announcement, Molecular Diagnostics

Biosearch Technologies Responds To China Influenza H7N9 Outbreak By Providing H7N9 Detection Panel

Posted on Mon, Apr 15, 2013 @ 06:00 AM

Biosearch Technologies, Inc. (Biosearch) announced today that the company has implemented a rapid response to the ...

Topics: Announcement, Product Information, Biodefense

Stellaris® Foundation Genes: GAPDH

Posted on Thu, Apr 11, 2013 @ 09:30 AM

Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA were among the first designed at ...

Topics: RNA FISH

Biosearch Technologies, UMDNJ Stellaris® Probe Alliance - NextGen Gene Expression™, SNP FISH™, and iceFISH™ in Research and Clinical Applications

Posted on Mon, Mar 18, 2013 @ 08:43 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Biosearch Technologies Announces Acquisition of European Companies DNA Technology and VitraBio

Posted on Thu, Feb 21, 2013 @ 06:00 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated, custom-manufactured oligonucleotides and ...

Topics: Announcement

Biosearch Technologies Launches Catalogued Stellaris™ RNA FISH Assays

Posted on Mon, Jun 18, 2012 @ 08:08 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Single molecule viral RNA analysis using Stellaris™ FISH technology

Posted on Wed, May 30, 2012 @ 01:00 PM

Image courtesy of: http://www.cdc.gov/h1n1flu/images.htm A cooperative effort between researchers at Mount Sinai ...

Topics: Biodefense, RNA FISH

Biosearch Technologies Appoints Uniscience as Brazilian Distributor

Posted on Tue, May 22, 2012 @ 08:16 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement

Biosearch Technologies Launches Improved RNA FISH Design Software

Posted on Mon, Mar 19, 2012 @ 07:54 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

qPCR Probes at work: Innovative CLIA test for NSCLC staging

Posted on Tue, Mar 06, 2012 @ 11:00 AM

Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently ...

Topics: Molecular Diagnostics, Real-time PCR

Factors affecting fluorophore performance in qPCR

Posted on Wed, Jan 11, 2012 @ 09:00 AM

A "Referral from the Doctor" Blog Article- In qPCR, fluorescent modified oligos may be either linear or non-linear in ...

Topics: Real-time PCR, Referral from the Doctor

Stellaris FISH Workshop at the AMP 2011

Posted on Tue, Nov 15, 2011 @ 01:53 PM

Join us at AMP 2011 on November 16th for a live demonstration of the Stellaris technology at the Gaylord Texan Resort ...

Topics: RNA FISH, Lab Method

The 'Monte Carlo' Effect in qPCR

Posted on Wed, Nov 09, 2011 @ 11:00 AM

A "Referral from the Doctor" Blog Article- The mathematical model of PCR is based on the assumption that each DNA ...

Topics: Referral from the Doctor

Blogging about Stellaris™ RNA FISH at Singlemoleculefish.com

Posted on Mon, Oct 24, 2011 @ 12:24 PM

Biosearch Technologies is starting a new sister blog at singlemoleculefish.com where all articles will focus on topics ...

Topics: Announcement, RNA FISH

Biosearch Technologies Announces Release of Custom Stellaris™ FISH Probes

Posted on Mon, Sep 12, 2011 @ 04:59 AM

Stellaris FISH advances research in cancer, developmental biology and pathology by resolving in situ messenger RNA into ...

Topics: RNA FISH

Fluorescence Quenching Mechanisms for Dual-Labeled Probes

Posted on Wed, Jun 29, 2011 @ 07:44 AM

A "Referral from the Doctor" Blog Article- Fluorescent probes are used in biochemical assays to monitor specific events ...

Topics: Real-time PCR, Referral from the Doctor

Special Summer Offer from Biosearch

Posted on Mon, Jun 13, 2011 @ 08:49 AM

Despite the unusually brisk May/June weather in California, Biosearch is welcoming the summer with a new promotion to ...

Topics: Announcement

Multiplexing with Xanthenes

Posted on Wed, Jun 08, 2011 @ 09:13 AM

A "Referral from the Doctor" Blog Article- Quantitative real-time PCR (qPCR) was developed as a means to detect the ...

Topics: Real-time PCR, Referral from the Doctor

qPCR Troubleshooting

Posted on Thu, May 05, 2011 @ 10:23 AM

A "Referral from the Doctor" Blog Article- Quantitative real-time PCR (qPCR) is based upon the fractional cycle number ...

Topics: Real-time PCR, Referral from the Doctor

Biosearch Technologies and Intelligent Medical Devices, Inc. (IMDx) Finalize cGMP Oligo Supply and Licensing Agreements for Molecular Diagnostic Testing (IVD) Products

Posted on Tue, Mar 15, 2011 @ 10:01 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

Holiday Savings at Biosearchtech.com!

Posted on Mon, Dec 06, 2010 @ 04:00 AM

Biosearch Technologies is once again offering a holiday promotion to our blog readers, Twitter followers, and Facebook ...

Topics: Announcement

The Latest Scientific Streak in Fashion

Posted on Thu, Dec 02, 2010 @ 10:12 AM

I’ve always wondered why scientists have earned themselves this infamous reputation of dressing poorly and ...

Topics: Announcement

Biosearch Technologies Licenses Access to the New CDC "PDM" H1N1 Signatures

Posted on Thu, Nov 18, 2010 @ 08:08 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Biodefense

Between ROX and a Hard Place

Posted on Wed, Nov 10, 2010 @ 09:12 AM

A "Referral from the Doctor" Blog Article- ROX in qPCR Quantitative real-time RT-PCR was developed as a means of ...

Topics: Real-time PCR, Referral from the Doctor

Biosearch Technologies and DuPont Qualicon Finalize Agreements for Food Safety Dx

Posted on Fri, Oct 29, 2010 @ 09:24 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Real-time PCR, Food Safety

Biosearch Technologies and Seegene Finalize Oligonucleotide Supply and BHQ®, CAL Fluor® and Quasar® Licensing Agreements

Posted on Wed, Oct 20, 2010 @ 08:12 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Real-time PCR

Biosearch Technologies Awarded Second Phase II Army SBIR Grant

Posted on Wed, Oct 13, 2010 @ 08:39 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Biodefense

Visit Biosearch at IVD Technology's Virtual Conference and Tradeshow

Posted on Thu, Sep 23, 2010 @ 02:32 PM

Biosearch Technologies is proud to sponsor the first IVD Technology Virtual Conference and Tradeshow. This free online ...

Topics: Announcement, Molecular Diagnostics

Biosearch Technologies Awarded Phase II Army SBIR Grant

Posted on Tue, Sep 21, 2010 @ 09:41 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Molecular Diagnostics

Biosearch Technologies Expands Licensing of QIAGEN Scorpions® Patents

Posted on Thu, Aug 12, 2010 @ 08:41 AM

Biosearch Technologies today announces that it has entered into a new license relationship with QIAGEN (NASDAQ: QIA, ...

Topics: Announcement, Real-time PCR, Product Information

Biosearch Technologies Signs Exclusive License for Single Molecule FISH Technologies from UMDNJ

Posted on Thu, Aug 05, 2010 @ 08:07 AM

Biosearch Technologies today announces the company has licensed exclusively from the University of Medicine and ...

Topics: Announcement

Taq Facts

Posted on Tue, Aug 03, 2010 @ 08:14 AM

A "Referral from the Doctor" Blog Article- When the polymerase chain reaction (PCR) was first described, the Klenow ...

Topics: Real-time PCR, Referral from the Doctor

PilotDx Oligos: En Route to IVD

Posted on Thu, Jul 22, 2010 @ 08:07 AM

It can be difficult to transition a product from research to commercialization. It’s simply not feasible to conduct ...

Topics: Molecular Diagnostics

Pipetting for qPCR

Posted on Wed, Jun 09, 2010 @ 08:41 AM

A "Referral from the Doctor" Blog Article- Research trends in laboratories today increasingly steer towards gene ...

Topics: Real-time PCR, Lab Method, Referral from the Doctor

Easier Online Ordering through RealTimeDesign™ Software

Posted on Wed, May 26, 2010 @ 08:32 AM

RealTimeDesign (RTD TM) Software from Biosearch Technologies is an easy to use, yet powerful assay design application ...

Topics: Real-time PCR, Design Services

Buy One qPCR Probe & Get One FREE

Posted on Fri, May 14, 2010 @ 09:21 AM

Buy one CAL Fluor® or Quasar® -BHQ® Probe and get a FREE ValuProbeTM BHQ Probe* and calibration standard ($190 in ...

Topics: Announcement, Real-time PCR

New! Quasar WS Protein Labeling Kit (beta)

Posted on Tue, May 04, 2010 @ 01:11 PM

Quasar® WS Protein Labeling Kits (beta) Biosearch Technologies is pleased to announce that we are offering protein ...

Topics: Product Information, Labeling Reagents

New Product Line! ValuPanel™ Reagents

Posted on Tue, Apr 06, 2010 @ 08:52 AM

We are pleased to introduce ValuPanel Reagents, a new product line of mission-critical probe and primer sets that ...

Topics: Announcement, Real-time PCR, Product Information, Biodefense

Black Hole Scorpion® Primers - Killer probes for qPCR

Posted on Wed, Mar 24, 2010 @ 08:57 AM

A "Referral from the Doctor" Blog Article- Scorpions®Primers are dual-labeled FRET probes that combine a Molecular ...

Topics: Real-time PCR, Product Information, Referral from the Doctor

Molecular Beacons - Lights in the storm

Posted on Wed, Mar 10, 2010 @ 11:05 AM

A "Referral from the Doctor" Blog Article- Molecular Beacons are a special type of dual-labeled oligonucleotide probe. ...

Topics: Real-time PCR, Referral from the Doctor

Biosearch Technologies Expands Licensing of Roche Patents to Manufacture Kits Targeting the in-vitro Diagnostic Industry

Posted on Tue, Mar 09, 2010 @ 09:37 AM

Biosearch Technologies today announces that the company has expanded its licenses from Roche Molecular Systems, Inc. ...

Topics: Announcement, Molecular Diagnostics

Biosearch Technologies Issued Two New Patents

Posted on Wed, Mar 03, 2010 @ 01:50 PM

Biosearch Technologies announced today that it has been awarded new patents related to luminescent metal chelate and ...

Topics: Announcement

Dual-labeled BHQ probes - Performance to “dye” for

Posted on Wed, Feb 24, 2010 @ 10:20 AM

A "Referral from the Doctor" Blog Article- A BHQ® probe is a dual-labeled oligonucleotide covalently labeled with a ...

Topics: Real-time PCR, Referral from the Doctor

This Year's MVP (Most Valuable Practice): Touchdown PCR

Posted on Thu, Feb 04, 2010 @ 10:39 AM

A "Referral from the Doctor" Blog Article- The aim of the Polymerase Chain Reaction (PCR) method is to amplify or ...

Topics: Real-time PCR, Referral from the Doctor

The Grand Ballet: Wine and Biotechnology

Posted on Wed, Jan 27, 2010 @ 11:15 AM

At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS laboratories (ETS) scientist Rich DeScenzo ...

Topics: Real-time PCR

An Alternative to DNAse I heat inactivation: LiCl precipitation

Posted on Wed, Jan 13, 2010 @ 10:04 AM

A "Referral from the Doctor" Blog Article- Genomic DNA contamination has been a hot topic for qPCR researchers since ...

Topics: Real-time PCR, Referral from the Doctor

A Quick Jump Start to Multiplexing qPCR

Posted on Wed, Jan 06, 2010 @ 10:01 AM

By now, you've no doubt read about the reductions in error, cost and time that can be achieved by multiplexing real ...

Topics: Real-time PCR, Design Services

Holiday Business Hours

Posted on Tue, Dec 22, 2009 @ 03:26 PM

Biosearch Technologies' facilities will be closed on 12/24, 12/25, 12/28, 12/31, and 1/1. We will be open during ...

Topics: Announcement

Slope Efficiency Equals Manageable and Corrected PCR

Posted on Wed, Dec 09, 2009 @ 12:01 PM

A "Referral from the Doctor" Blog Article- ε = m.c.2 (shall I explain? slope efficiency equals manageable and ...

Topics: Real-time PCR, Referral from the Doctor

Holiday Promotion at Biosearchtech.com

Posted on Thu, Dec 03, 2009 @ 08:57 AM

To celebrate the end of the year, we are offering a holiday promotion to our blog readers, Twitter followers, and ...

Topics: Announcement

On the Set of "Making of the Swine Flu Test Kit - Inside Biosearch Technologies"

Posted on Thu, Nov 19, 2009 @ 08:29 AM

Biosearch Technologies recently launched a video, Making of the Swine Flu Test Kit - Inside Biosearch Technologies, ...

Topics: Molecular Diagnostics, Real-time PCR, Biodefense

Bringing Back a Champion: Competitive Quantitative Real-time RT-PCR

Posted on Wed, Nov 18, 2009 @ 08:08 AM

A "Referral from the Doctor" Blog Article- Competitive qRT-PCR has become a lost art. Early titans of probe-based PCR ...

Topics: Real-time PCR, Referral from the Doctor

BIOSEARCH TECHNOLOGIES TAKES LICENSE TO CDC H1N1 SIGNATURES AND INFLUENZA A SUB-TYPING PATENT

Posted on Wed, Nov 04, 2009 @ 07:47 AM

Biosearch Technologies announced today that the company has licensed from the CDC the novel H1N1 Influenza signatures ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR, Biodefense

Micronics Acquires License to Biosearch Technologies’ Nucleic Acid Assay Chemistries

Posted on Wed, Oct 28, 2009 @ 01:16 PM

Micronics, Inc., a leading developer of point-of-care molecular diagnostic products, announced today that it has ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

The New Favorite Reference Gene: 36B4, a.k.a. RPLP0

Posted on Wed, Oct 14, 2009 @ 08:06 AM

A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...

Topics: Real-time PCR, Custom Oligos, Referral from the Doctor

DoD Issues SBIR Grants to Biosearch Technologies

Posted on Thu, Oct 08, 2009 @ 08:13 AM

Biosearch Technologies has been selected for two Small Business Innovative Research (SBIR) grants from the Department ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

What Genes are Hot, What Genes are Not

Posted on Wed, Oct 07, 2009 @ 02:41 PM

A "Referral from the Doctor" Blog Article- Top 10 Reference Genes for probe-based Real-time PCR in 2009: • Acidic ...

Topics: Real-time PCR, Referral from the Doctor

FDA Awards Biosearch Technologies $3.4 MM Contract

Posted on Mon, Oct 05, 2009 @ 07:48 AM

The FDA has awarded Biosearch Technologies a five year contract for the development of multiplexed, fluorescent ...

Topics: Molecular Diagnostics, Custom Oligos, Food Safety, Biodefense

Biosearch Technologies Takes License to the Roche 5' Nuclease Patents

Posted on Thu, Oct 01, 2009 @ 07:08 AM

Biosearch Technologies has ground breaking news to announce today. We licensed a family of patents covering practice ...

Topics: Announcement, Molecular Diagnostics

Labeling Oligos with Internal BHQ Dyes

Posted on Tue, Sep 29, 2009 @ 08:16 AM

When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR. When the ...

Topics: Real-time PCR, Product Information, Custom Oligos

Biosearch Technologies' Response to the Recently Filed Complaint Alleging Patent Infringement

Posted on Tue, Sep 22, 2009 @ 03:23 PM

Biosearch Technologies has received a complaint for alleged patent infringement filed in the U.S. District Court for ...

Topics: Announcement

Salt-Free Primer Pair Option Now Available

Posted on Tue, Sep 22, 2009 @ 08:08 AM

Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...

Topics: Real-time PCR, Product Information, Custom Oligos

Biosearch Technologies is adding more COLOR to qPCR

Posted on Mon, Sep 21, 2009 @ 02:07 PM

Since its introduction in 2005, the ValuProbe BHQ Probe has become Biosearch Technologies' most popular product sold to ...

Topics: Announcement, Real-time PCR, Product Information

Biosearch Technologies Embraces Social Networking

Posted on Thu, Sep 17, 2009 @ 09:48 PM

Want to keep up with the latest at Biosearch Technologies? Or do you just want to familiarize yourself with the ...

Topics: Announcement

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