How to select an effective nucleic acid isolation method for human diagnostics

How to select an effective nucleic acid isolation method for human diagnostics

Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality isolation of genetic material from diverse sample types. There are many extraction and purification technologies available. Before deciding which isolation method best suits your application, read this blog that walks you through key considerations...

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Five ways controls can demystify your Stellaris™ RNA FISH experiment

Posted on Sun, Jan 23, 2022 @ 06:14 AM

Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time interrogating a sample with a new ...
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Topics: RNA FISH, General science

Warning! Pitfalls ahead: How to avoid the most common Stellaris RNA FISH mistakes

Posted on Tue, May 29, 2018 @ 10:32 AM

Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice ...
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Topics: RNA FISH, Genomics

Shining a light on gene expression and regulation one cell at a time

Posted on Thu, Apr 19, 2018 @ 12:51 PM

To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data ...
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Topics: RNA FISH, Genomics

In case you missed it: Stellaris RNA FISH lunch-and-learn

Posted on Tue, Jan 16, 2018 @ 10:35 AM

Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous ...
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Topics: RNA FISH, Genomics

Lunch & Learn: Stellaris RNA FISH

Posted on Thu, Jul 06, 2017 @ 10:07 AM

Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our ...
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Topics: RNA FISH, Genomics, General science

Shining a light on how Zika virus may spread from mothers to human fetuses

Posted on Mon, Mar 06, 2017 @ 10:37 AM

New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus ...
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Topics: RNA FISH, Disease detection, Human healthcare, General science

A Stellar-is Year in the Making

Posted on Wed, Dec 07, 2016 @ 10:05 AM

 It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a ...
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Topics: RNA FISH, Genomics, General science

Imaging Stellaris Assays Part III: Creating Professional, Publication-ready Images

Posted on Thu, Mar 10, 2016 @ 04:00 PM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone over ...
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Topics: RNA FISH, General science

Designing Stellaris RNA FISH Probes Part I: Increasing Probe Count

Posted on Thu, Jan 14, 2016 @ 04:00 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells and ...
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Topics: RNA FISH, General science

Imaging Stellaris Assays Part II: How to Acquire Stunning Images

Posted on Thu, Sep 24, 2015 @ 04:30 PM

Here we continue our “Imaging Stellaris Assays” blog series.  We last left off talking about the most important ...
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Topics: RNA FISH, General science

Runaway RNA Stays Put

Posted on Thu, Sep 17, 2015 @ 04:00 PM

The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the ...
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Topics: RNA FISH, General science

Imaging Stellaris Assays Part I: Get to Know Your Microscope

Posted on Thu, Aug 27, 2015 @ 07:00 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of ...
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Topics: RNA FISH, General science

And the Consensus (Sequence) is...

Posted on Thu, Jun 11, 2015 @ 04:31 PM

Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...
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Topics: RNA FISH, qPCR, Human healthcare, General science

Research Highlight: Bringing Vision Research into Focus

Posted on Thu, May 28, 2015 @ 04:14 PM

Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers ...
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Topics: RNA FISH, General science

FISH-ing for Fusions: A unique approach to fusion gene mRNA & pre-mRNA detection in cancer

Posted on Fri, May 15, 2015 @ 03:00 PM

This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia, PA ...
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Topics: RNA FISH, General science

The 4Cs of Stellaris® RNA FISH Buffers

Posted on Thu, Feb 26, 2015 @ 04:00 PM

Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its ...
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Topics: RNA FISH, General science

Unraveling the Neural Web: Stellaris® RNA FISH for Neuroscience Research

Posted on Thu, Nov 13, 2014 @ 05:45 PM

Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or mixed ...
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Topics: RNA FISH, General science

RT-qPCR and the Stellaris FISH Method

Posted on Fri, Apr 26, 2013 @ 12:32 PM

A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...
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Topics: RNA FISH, qPCR, Human healthcare, General science

Stellaris® Foundation Genes: GAPDH

Posted on Thu, Apr 11, 2013 @ 11:30 AM

Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA were among the first designed at ...
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Topics: RNA FISH, General science

Biosearch Technologies, UMDNJ Stellaris® Probe Alliance - NextGen Gene Expression™, SNP FISH™, and iceFISH™ in Research and Clinical Applications

Posted on Mon, Mar 18, 2013 @ 10:43 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...
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Topics: RNA FISH, General science

Biosearch Technologies Launches Catalogued Stellaris™ RNA FISH Assays

Posted on Mon, Jun 18, 2012 @ 10:08 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...
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Topics: RNA FISH, General science

Single molecule viral RNA analysis using Stellaris™ FISH technology

Posted on Wed, May 30, 2012 @ 03:00 PM

  Image courtesy of: http://www.cdc.gov/h1n1flu/images.htm A cooperative effort between researchers at Mount Sinai ...
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Topics: RNA FISH, General science

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LGC, Biosearch Technologies is the complete Genomics portfolio from LGC. Providing genomic analysis tools, instrumentation and services to the genomic scientific discovery sector worldwide, with focus on across ag bio, pharma and molecular diagnostics. Visit our home page to view our products and services.

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