The BiosearchTech Blog

Warning! Pitfalls ahead: How to avoid the most common Stellaris RNA FISH mistakes

Posted on Tue, May 29, 2018 @ 08:32 AM

Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice ...

Topics: RNA FISH, Genomics

Shining a light on gene expression and regulation one cell at a time

Posted on Thu, Apr 19, 2018 @ 10:51 AM

To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data ...

Topics: RNA FISH, Genomics

In case you missed it: Stellaris RNA FISH lunch-and-learn

Posted on Tue, Jan 16, 2018 @ 08:35 AM

Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous ...

Topics: RNA FISH, Genomics

Lunch & Learn: Stellaris RNA FISH

Posted on Thu, Jul 06, 2017 @ 08:07 AM

Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our ...

Topics: RNA FISH, Genomics

Shining a light on how Zika virus may spread from mothers to human fetuses

Posted on Mon, Mar 06, 2017 @ 08:37 AM

New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus ...

Topics: RNA FISH, Disease detection

A Stellar-is Year in the Making

Posted on Wed, Dec 07, 2016 @ 08:05 AM

It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a ...

Topics: RNA FISH, Genomics

Imaging Stellaris Assays Part III: Creating Professional, Publication-ready Images

Posted on Thu, Mar 10, 2016 @ 02:00 PM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone over ...

Topics: RNA FISH

Designing Stellaris RNA FISH Probes Part I: Increasing Probe Count

Posted on Thu, Jan 14, 2016 @ 02:00 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells and ...

Topics: RNA FISH

Imaging Stellaris Assays Part II: How to Acquire Stunning Images

Posted on Thu, Sep 24, 2015 @ 02:30 PM

Here we continue our “Imaging Stellaris Assays” blog series. We last left off talking about the most important ...

Topics: RNA FISH

Runaway RNA Stays Put

Posted on Thu, Sep 17, 2015 @ 02:00 PM

The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the ...

Topics: RNA FISH

Imaging Stellaris Assays Part I: Get to Know Your Microscope

Posted on Thu, Aug 27, 2015 @ 05:00 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of ...

Topics: RNA FISH

And the Consensus (Sequence) is...

Posted on Thu, Jun 11, 2015 @ 02:31 PM

Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...

Topics: Real-time PCR, RNA FISH

Research Highlight: Bringing Vision Research into Focus

Posted on Thu, May 28, 2015 @ 02:14 PM

Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers ...

Topics: RNA FISH

FISH-ing for Fusions: A unique approach to fusion gene mRNA & pre-mRNA detection in cancer

Posted on Fri, May 15, 2015 @ 01:00 PM

This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia, PA ...

Topics: RNA FISH

Research Highlight: Localizing long non-coding RNA (lncRNA)

Posted on Thu, Mar 12, 2015 @ 02:00 PM

A recent paper published in Molecular Cell by Dimitrova et al. from the lab of Dr. Tyler Jacks at MIT, used Stellaris® ...

Topics: RNA FISH

The 4Cs of Stellaris® RNA FISH Buffers

Posted on Thu, Feb 26, 2015 @ 02:00 PM

Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its ...

Topics: RNA FISH

Unraveling the Neural Web: Stellaris® RNA FISH for Neuroscience Research

Posted on Thu, Nov 13, 2014 @ 03:45 PM

Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or mixed ...

Topics: RNA FISH

RT-qPCR and the Stellaris FISH Method

Posted on Fri, Apr 26, 2013 @ 10:32 AM

A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...

Topics: Real-time PCR, RNA FISH

Stellaris® Foundation Genes: GAPDH

Posted on Thu, Apr 11, 2013 @ 09:30 AM

Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA were among the first designed at ...

Topics: RNA FISH

Biosearch Technologies, UMDNJ Stellaris® Probe Alliance - NextGen Gene Expression™, SNP FISH™, and iceFISH™ in Research and Clinical Applications

Posted on Mon, Mar 18, 2013 @ 08:43 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: RNA FISH

Biosearch Technologies Launches Catalogued Stellaris™ RNA FISH Assays

Posted on Mon, Jun 18, 2012 @ 08:08 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: RNA FISH

Single molecule viral RNA analysis using Stellaris™ FISH technology

Posted on Wed, May 30, 2012 @ 01:00 PM

Image courtesy of: http://www.cdc.gov/h1n1flu/images.htm A cooperative effort between researchers at Mount Sinai ...

Topics: RNA FISH

Blogging about Stellaris™ RNA FISH at Singlemoleculefish.com

Posted on Mon, Oct 24, 2011 @ 12:24 PM

Biosearch Technologies is starting a new sister blog at singlemoleculefish.com where all articles will focus on topics ...

Topics: RNA FISH

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Considerations for RT-qPCR in molecular point of care testing devices