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Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of...
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- Agrigenomics
- Disease detection
- General science
- Genomics
- Molecular diagnostics
- NGS-based genotyping
- Nucleic acid extraction
- Nucleic acid therapeutics
- Oligo synthesis and modifications
- PCR-based genotyping
- qPCR
- RNA FISH
- SARS-CoV-2
Human Healthcare
Applied Agrigenomics
General Science
Molecular diagnostics Oligo synthesis and modifications qPCR
Updated : Fri, May 5, 2023 @ 2:34 PM
How does a BHQ dye contribute to producing superior data from your assays?
Updated : Wed, December 14, 2022 @ 1:54 PM
When the polymerase chain reaction (PCR) was first described, the Klenow...
Molecular diagnostics Oligo synthesis and modifications qPCR
Updated : Tue, May 9, 2023 @ 10:40 AM
Let the application be your guide when deciding between LNA, MGB and BHQplus
The...
Updated : Wed, March 30, 2022 @ 4:00 PM
While both centralised and decentralised molecular diagnostics (MDx) testing...
Agrigenomics qPCR PCR-based genotyping
Updated : Wed, March 9, 2022 @ 1:05 AM
African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop...
Updated : Fri, April 15, 2022 @ 8:58 PM
The COVID-19 pandemic has accelerated the uptake of point of care testing...
Updated : Fri, February 11, 2022 @ 10:58 PM
But measurement science could help steer us in a better, more informed...
Agrigenomics qPCR PCR-based genotyping
Updated : Thu, January 12, 2023 @ 5:10 PM
Rice is the primary staple for more than half the world's population.1 With...
Updated : Thu, February 3, 2022 @ 6:10 PM
When results from your qPCR assays aren’t quite what you expected, it can be...
Molecular diagnostics qPCR SARS-CoV-2
Updated : Thu, March 31, 2022 @ 3:24 PM
In September 2021, Delta persists as the most prevalent variant worldwide1 due...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:44 PM
As countries worldwide begin to ease lockdown restrictions during the pandemic...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Fri, December 18, 2020 @ 8:49 PM
It may seem strange that a company known for transforming the global seed...
Updated : Mon, September 19, 2022 @ 2:07 PM
LGC's Genomics Division has signed a memorandum of understanding (MOU) with...
Updated : Mon, September 19, 2022 @ 2:15 PM
It seems everyone wants to do more with less, and automate the process as...
Updated : Wed, March 29, 2023 @ 11:04 AM
As the Zika virus outbreak spreads, a wave of international concern has grown,...
Molecular diagnostics Oligo synthesis and modifications qPCR
Updated : Wed, December 14, 2022 @ 5:04 PM
OLIGO SYNTHESIS PHOTO GLIMPSE
We’ve recently captured our talented...
Updated : Mon, April 24, 2023 @ 8:54 AM
LGC Biosearch Technologies has developed a new qPCR probe format powered by...
Oligo synthesis and modifications qPCR
Updated : Wed, March 29, 2023 @ 10:54 AM
This week, we continue our Know your oligo mod blog series and we will focus...
Updated : Fri, November 13, 2015 @ 9:25 PM
Studying the expression level of RNA transcripts is often complicated by the...
Updated : Fri, November 13, 2015 @ 10:40 PM
In the setup of a qPCR experiment, one of the first decisions to make is...
Updated : Mon, November 16, 2015 @ 5:30 PM
In a webinar linked below, Dr. James Willey describes a two colour...
Updated : Mon, September 19, 2022 @ 2:12 PM
Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15...
Updated : Tue, March 28, 2023 @ 9:02 PM
Biosearch Technologies has launched qPCRdesign.com, a microsite targeted...
Oligo synthesis and modifications qPCR
Updated : Tue, October 14, 2014 @ 10:21 PM
Different oligonucleotide manufacturers deliver probes and primers in a...
Updated : Mon, September 19, 2022 @ 2:13 PM
The largest recorded Ebola Virus Disease outbreak in history continues to...
Updated : Mon, September 19, 2022 @ 2:12 PM
Don’t waste time performing an extra step. Cut back on pipetting and order...
Updated : Tue, March 21, 2023 @ 3:52 PM
Do you remember when the most popular method of DNA amplification involved...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Quantitative reverse...
Updated : Wed, October 1, 2014 @ 4:51 PM
Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of...
Updated : Fri, October 21, 2022 @ 10:24 AM
Fluorophores are molecules that can absorb light energy in a process called...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Fluorescent probes are used in...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Quantitative real-time PCR...
Updated : Thu, May 11, 2023 @ 10:06 AM
If you run quantitative real-time PCR (qPCR) assays, the chances are that...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
ROX in qPCR
Quantitative...
Updated : Mon, September 19, 2022 @ 2:14 PM
A "Referral from the Doctor" Blog Article-
Research trends in laboratories...
Updated : Thu, March 23, 2023 @ 11:57 AM
Scorpions™ Primers are dual-labeled FRET probes that combine a Molecular...
Updated : Mon, March 20, 2023 @ 9:54 PM
Molecular Beacons are a special type of dual-labeled oligonucleotide probe....
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article
A BHQ® probe is a dual-labeled...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
The aim of the Polymerase...
Updated : Wed, October 1, 2014 @ 4:38 PM
At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS...
Updated : Wed, December 14, 2022 @ 4:20 PM
A "Referral from the Doctor" Blog Article-
Genomic DNA contamination has...
Updated : Thu, September 22, 2022 @ 5:16 PM
By now, you've no doubt read about the reductions in error, cost and time...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
ε = m.c.2 (shall I explain?...
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Competitive qRT-PCR has become...
Oligo synthesis and modifications qPCR
Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Ribosomes are comprised of two...Updated : Mon, September 19, 2022 @ 2:10 PM
A "Referral from the Doctor" Blog Article-
Top 10 Reference Genes for...
Oligo synthesis and modifications qPCR
Updated : Fri, January 13, 2023 @ 11:38 AM
When to use an internal Black Hole Quencher (BHQ) label in a...
Oligo synthesis and modifications qPCR
Updated : Mon, September 19, 2022 @ 2:12 PM
Biosearch Technologies will now be offering the option of salt-free...
Molecular diagnostics Genomics
Image credit: HIV Reverse Transcriptase. RCSB Protein Data Bank. The Wellcome Collection.
Disease detection Nucleic acid therapeutics
While RNA-based therapeutics are taking the biotechnology world by storm following the rapid development of the COVID-19 vaccines, the next generation of...
Oligo synthesis and modifications Nucleic acid therapeutics
Considering bringing oligo synthesis in-house? Here are some commonly asked questions that we receive, grouped into four sections. You can jump to a section...
The recent Nobel Prize awarded to Katalin Karikó and Drew Weissman underlined the impact their breakthroughs in mRNA technology had in combating COVID-19....
Molecular diagnostics Disease detection
As the world scrambled to rapidly expand PCR testing capacity in 2020, it became increasingly clear that there was a need for cheaper, simpler, quicker...
Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of antimicrobial agents that accelerates the...
Oligo synthesis and modifications Nucleic acid therapeutics
Over the last few decades, researchers have made impressive strides in developing methods to overcome the delivery, stability, and specificity challenges of...
Molecular diagnostics Nucleic acid extraction
Whether you’re working with samples for PCR or sequencing, it's worth questioning what type of extraction or purification method would work well with your...
Updated : Fri, May 26, 2023 @ 10:18 AM
Designing a new assay and scaling it for commercial use takes thoughtful planning, foresight, and engagement with...
Updated : Tue, May 9, 2023 @ 11:03 AM
When it comes to oligonucleotide therapeutics, the challenge has always been how to deliver an intact oligo to the right...
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Fri, May 5, 2023 @ 2:34 PM
How does a BHQ dye contribute to producing superior data from your assays?
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Mon, June 26, 2023 @ 10:24 AM
Oligonucleotide therapeutics have unlocked new treatment possibilities for rare and fatal diseases often associated...
Molecular diagnostics SARS-CoV-2 Disease detection
Updated : Tue, May 9, 2023 @ 10:57 AM
We were delighted to attend the Association for Molecular Pathology (AMP) 2022 annual meeting, held in Phoenix, Arizona...
Molecular diagnostics Oligo synthesis and modifications
Updated : Tue, May 9, 2023 @ 11:01 AM
Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection...
Molecular diagnostics Nucleic acid extraction General science
Updated : Tue, May 9, 2023 @ 11:05 AM
Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality...
Oligo synthesis and modifications Nucleic acid therapeutics General science
Updated : Tue, August 9, 2022 @ 7:10 PM
New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Tue, May 9, 2023 @ 10:40 AM
Let the application be your guide when deciding between LNA, MGB and BHQplus
The many different chemistries available...
Molecular diagnostics Disease detection
Updated : Wed, March 22, 2023 @ 1:59 PM
Since 13 May 2022, reports of monkeypox cases began to appear globally in regions not endemic to the monkeypox virus.1...
SARS-CoV-2 Nucleic acid extraction Disease detection General science
Updated : Fri, December 16, 2022 @ 3:39 PM
Since early 2020, diagnostic laboratories have had to manage patient sample quantities being in a state of flux....
Updated : Tue, March 21, 2023 @ 3:23 PM
What’s changed for clinical labs as we enter the third year of COVID-19 testing?
COVID-19, the illness caused by...
Molecular diagnostics qPCR General science
Updated : Wed, March 30, 2022 @ 4:00 PM
While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient...
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Tue, March 21, 2023 @ 3:46 PM
This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of...
Molecular diagnostics qPCR General science
Updated : Fri, April 15, 2022 @ 8:58 PM
The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests...
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Tue, March 21, 2023 @ 3:44 PM
This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the...
qPCR SARS-CoV-2 General science
Updated : Fri, February 11, 2022 @ 10:58 PM
But measurement science could help steer us in a better, more informed direction
COVID-19 tests can indicate the...
Updated : Tue, January 11, 2022 @ 6:00 PM
What’s changed for clinical labs as we enter the third year of COVID-19 testing?
COVID-19, the illness caused by...
Updated : Tue, December 28, 2021 @ 3:30 PM
What’s changed for clinical labs as we enter the third year of COVID-19 testing?
COVID-19, the illness caused by...
Molecular diagnostics SARS-CoV-2
Updated : Wed, March 22, 2023 @ 2:01 PM
The emergence of the Omicron lineage has quickly escalated to be a variant of concern by the World Health Organization -
Updated : Thu, March 9, 2023 @ 5:39 PM
What’s changed for clinical labs as we enter the third year of COVID-19 testing?
Molecular diagnostics SARS-CoV-2
Updated : Fri, December 10, 2021 @ 2:34 AM
On 22 November 2021, The Network for Genomics Surveillance in South Africa detected a new SARS-CoV-2 variant, named...
| We're excited to announce that the proposal to extend certain key provisions of the In Vitro Diagnostic Regulation (IVDR) (EU) 2017/746 has been adopted... |
Molecular diagnostics SARS-CoV-2 Disease detection
Updated : Tue, November 30, 2021 @ 10:29 PM
A fourth wave of COVID-19 has already emerged in many countries and a newly classified variant of concern, Omicron...
Molecular diagnostics Oligo synthesis and modifications
Updated : Tue, January 25, 2022 @ 10:23 PM
This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into...
Molecular diagnostics SARS-CoV-2
Updated : Thu, October 14, 2021 @ 10:01 PM
SARS-CoV-2 mutations and associated new variants are being reported regularly in the media and scientific...
Molecular diagnostics qPCR SARS-CoV-2 General science
Updated : Thu, March 31, 2022 @ 3:24 PM
In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges...
Updated : Wed, September 15, 2021 @ 4:40 AM
A shortcut to understanding how to prepare for IVDR
In today’s global environment, even small regulatory changes in...
Molecular diagnostics SARS-CoV-2
Updated : Wed, November 9, 2022 @ 8:20 PM
The COVID-19 pandemic brought tremendous change to the molecular diagnostics (MDx) industry, delivering opportunities...
Updated : Thu, September 29, 2022 @ 7:57 PM
As SARS-CoV-2 variants continue to threaten public health, officials are looking beyond clinical tests to track...
Updated : Thu, December 16, 2021 @ 6:46 PM
Emerging SARS-CoV-2 variants of concern and variants of interest are defined by agencies such as the World Health...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Thu, March 9, 2023 @ 5:37 PM
As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to...
Molecular diagnostics SARS-CoV-2
Updated : Thu, March 9, 2023 @ 5:34 PM
Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Thu, February 3, 2022 @ 4:39 PM
Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:45 PM
Following up with the panelists from our recent COVID-19 webinar, Part 3 of 3
In the previous two blog posts in this...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:42 PM
Following up with the panelists from our recent COVID-19 webinar, Part 2 of 3
In the face of a rapidly evolving...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:45 PM
Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3
The COVID-19 pandemic has presented...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:44 PM
As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal”...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Fri, December 18, 2020 @ 8:49 PM
It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned...
Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 General science
Updated : Wed, March 22, 2023 @ 1:52 PM
We’re not rejecting you, just your oligo
PCR is arguably one of the most enabling technologies of modern molecular...
Molecular diagnostics SARS-CoV-2
Updated : Wed, November 25, 2020 @ 8:23 PM
On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they...
Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:44 PM
In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Tue, March 21, 2023 @ 3:41 PM
*Since the original publication of this blog, LGC Biosearch Technologies is now the only acceptable commercial supplier...
Molecular diagnostics Genomics SARS-CoV-2
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Molecular diagnostics Next generation sequencing (NGS)
Updated : Tue, October 11, 2022 @ 8:43 PM
The development of new genomic sequencing techniques and bioinformatics analysis in the last decade has led to...
Genomics PCR-based genotyping Disease detection General science
Updated : Mon, September 19, 2022 @ 2:14 PM
3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious...
RNA FISH Disease detection General science
Updated : Mon, March 6, 2017 @ 4:37 PM
New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus spreads...
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Wed, December 14, 2022 @ 5:04 PM
OLIGO SYNTHESIS PHOTO GLIMPSE
We’ve recently captured our talented manufacturing teams hard at work building...
Molecular diagnostics qPCR General science
Updated : Mon, September 19, 2022 @ 2:13 PM
The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This...
Molecular diagnostics qPCR General science
Updated : Wed, October 1, 2014 @ 4:51 PM
Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently...
Updated : Mon, September 19, 2022 @ 2:07 PM
Biosearch Technologies is proud to sponsor the first IVD Technology Virtual Conference and Tradeshow. This free...
Updated : Wed, October 1, 2014 @ 4:42 PM
It can be difficult to transition a product from research to commercialization. It’s simply not feasible to conduct...
Agrigenomics NGS-based genotyping
How does genomic selection increase profitability?
Livestock farmers’ and breeders’ profitability is directly related to the quality of their stock. But this...
Agrigenomics NGS-based genotyping
Every year over 1.5 million tonnes of blueberries and over half a million tonnes of cranberries are produced. This is expected to rise significantly over the...
Updated : Thu, June 1, 2023 @ 4:09 PM
Oil palm, Elaeis guineensis Jacq., is the most productive oil crop in the world1 supplying around 40% of all globally...
Agrigenomics PCR-based genotyping
Updated : Tue, May 9, 2023 @ 10:48 AM
Around 159,200 tonnes of strawberries are produced annually in Japan across 5,020 ha in various regions around the...
Agrigenomics PCR-based genotyping
Updated : Wed, March 22, 2023 @ 1:48 PM
Genotyping plants can be a complex and frustrating process
Agrigenomics PCR-based genotyping
Updated : Wed, March 22, 2023 @ 1:22 PM
Modern agriculture faces unprecedented challenges: increasing global temperatures, water scarcity, less arable land to...
Updated : Mon, April 17, 2023 @ 1:33 PM
This is the first blog in a two-part series exploring solutions for infectious diseases in aquaculture. This blog post...
Agrigenomics qPCR PCR-based genotyping General science
Updated : Wed, March 9, 2022 @ 1:05 AM
African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop that is used widely in food, medicines,...
Agrigenomics qPCR PCR-based genotyping
Updated : Thu, January 12, 2023 @ 5:10 PM
Rice is the primary staple for more than half the world's population.1 With so many people relying on the crop for...
Agrigenomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Tue, December 7, 2021 @ 10:11 PM
The decisions made by molecular breeding programmes have a substantial impact on the world around us, from...
Agrigenomics NGS-based genotyping
Updated : Fri, June 30, 2023 @ 2:19 PM
Many cultivated crops with agronomic significance, including wheat, peanut, oat, banana, potato, coffee, blueberry and...
Agrigenomics PCR-based genotyping Nucleic acid extraction
Updated : Tue, September 7, 2021 @ 7:59 PM
Aquaculture breeding programmes adopt genomic technologies, including genotyping, to increase genetic gain for...
Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction
Updated : Thu, August 12, 2021 @ 11:51 PM
Informed plant breeding decisions help drive the field of agrigenomics towards ever-increasing agricultural...
Agrigenomics Nucleic acid extraction
Updated : Wed, August 4, 2021 @ 9:34 PM
A common mistake when initiating an agrigenomics project is failing to consider specific sample composition before...
Agrigenomics Genomics General science
Updated : Wed, December 14, 2022 @ 1:44 PM
The global demand for fish and fish products continues to increase as consumers focus on health-conscious ways to...
Agrigenomics Genomics NGS-based genotyping
Updated : Fri, November 20, 2020 @ 5:16 PM
In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted...
Updated : Wed, October 7, 2020 @ 4:33 PM
“In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish...
Agrigenomics Genomics PCR-based genotyping
Updated : Fri, September 11, 2020 @ 9:52 PM
Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her...
Agrigenomics Genomics PCR-based genotyping
Updated : Tue, July 14, 2020 @ 1:30 PM
Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique...
Genomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Wed, April 1, 2020 @ 8:12 PM
Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and...
Genomics PCR-based genotyping NGS-based genotyping
Updated : Mon, January 13, 2020 @ 5:08 PM
Best practice in sample collection for SeqSNP targeted genotyping by sequencing projects
When good goes in, great...
Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Wed, May 1, 2019 @ 3:59 PM
Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the...
Agrigenomics PCR-based genotyping Next generation sequencing (NGS) NGS-based genotyping
Updated : Fri, May 19, 2023 @ 8:53 AM
“Experience of artificial fertilisation, such as is effected with ornamental plants in order to obtain new variations in...
Agrigenomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Thu, May 25, 2023 @ 11:32 AM
Plant and animal breeding programmes often take generations to improve quality and yield but using a genotyping protocol...
Updated : Wed, January 9, 2019 @ 5:03 PM
Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays
Agrigenomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Tue, December 11, 2018 @ 4:32 PM
Food security is a major global threat and traditional methods of plant and animal breeding will not be sufficient...
Updated : Thu, July 26, 2018 @ 4:41 PM
Diversity is the spice of life and is also key to breeding rice that delivers increased yields. Rice is a crucial staple...
Agrigenomics Genomics NGS-based genotyping General science
Updated : Mon, September 19, 2022 @ 2:16 PM
With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the...
Agrigenomics Genomics PCR-based genotyping
Updated : Wed, November 22, 2017 @ 1:44 PM
Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global...
Agrigenomics Genomics PCR-based genotyping
Updated : Tue, July 10, 2018 @ 9:08 PM
Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5...
Genomics PCR-based genotyping Disease detection General science
Updated : Mon, September 19, 2022 @ 2:14 PM
3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious...
Genomics PCR-based genotyping General science
Updated : Wed, February 15, 2017 @ 4:23 PM
Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand...
Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science
Updated : Wed, January 18, 2017 @ 2:13 PM
Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable...
Updated : Mon, January 9, 2017 @ 3:20 PM
Screen more markers faster and bring crops with superior traits to the market quicker.
![A Complete Ecosystem to Accelerate Breeding Programs [Infographic]](http://blog.biosearchtech.com/hubfs/images/ecosystem-hero-banner1600x712.jpg)
Updated : Tue, June 28, 2016 @ 9:00 PM
Modern breeding methods rely on the identification and utilization of molecular markers associated with traits...
qPCR PCR-based genotyping General science
Updated : Mon, September 19, 2022 @ 2:12 PM
Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in...
Molecular diagnostics Genomics
Image credit: HIV Reverse Transcriptase. RCSB Protein Data Bank. The Wellcome Collection.
Oligo synthesis and modifications Nucleic acid therapeutics
Considering bringing oligo synthesis in-house? Here are some commonly asked questions that we receive, grouped into four sections. You can jump to a section...
Oligo synthesis and modifications General science
Labelling, linking or modifying biomolecules used to be a laborious process, requiring customised complex synthetic pathways that yield little product....
Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of antimicrobial agents that accelerates the...
Oligo synthesis and modifications Nucleic acid therapeutics
Over the last few decades, researchers have made impressive strides in developing methods to overcome the delivery, stability, and specificity challenges of...
Molecular diagnostics Nucleic acid extraction
Whether you’re working with samples for PCR or sequencing, it's worth questioning what type of extraction or purification method would work well with your...
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Fri, May 5, 2023 @ 2:34 PM
How does a BHQ dye contribute to producing superior data from your assays?
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Mon, June 26, 2023 @ 10:24 AM
Oligonucleotide therapeutics have unlocked new treatment possibilities for rare and fatal diseases often associated...
Oligo synthesis and modifications General science
Updated : Tue, May 9, 2023 @ 10:51 AM
In the next edition of the “Know your oligo mod” series, we look at a universal base analogue for oligonucleotide...
Molecular diagnostics Oligo synthesis and modifications
Updated : Tue, May 9, 2023 @ 11:01 AM
Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection...
Molecular diagnostics Nucleic acid extraction General science
Updated : Tue, May 9, 2023 @ 11:05 AM
Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality...
Updated : Wed, December 14, 2022 @ 1:54 PM
When the polymerase chain reaction (PCR) was first described, the Klenow fragment of Escherichia coli DNA...
Oligo synthesis and modifications Nucleic acid therapeutics General science
Updated : Tue, August 9, 2022 @ 7:10 PM
New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Tue, May 9, 2023 @ 10:40 AM
Let the application be your guide when deciding between LNA, MGB and BHQplus
The many different chemistries available...
SARS-CoV-2 Nucleic acid extraction Disease detection General science
Updated : Fri, December 16, 2022 @ 3:39 PM
Since early 2020, diagnostic laboratories have had to manage patient sample quantities being in a state of flux....
Molecular diagnostics qPCR General science
Updated : Wed, March 30, 2022 @ 4:00 PM
While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient...
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Tue, March 21, 2023 @ 3:46 PM
This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of...
Agrigenomics qPCR PCR-based genotyping General science
Updated : Wed, March 9, 2022 @ 1:05 AM
African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop that is used widely in food, medicines,...
Molecular diagnostics qPCR General science
Updated : Fri, April 15, 2022 @ 8:58 PM
The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests...
Oligo synthesis and modifications Nucleic acid therapeutics
Updated : Tue, March 21, 2023 @ 3:44 PM
This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the...
qPCR SARS-CoV-2 General science
Updated : Fri, February 11, 2022 @ 10:58 PM
But measurement science could help steer us in a better, more informed direction
COVID-19 tests can indicate the...
Oligo synthesis and modifications
Updated : Tue, January 25, 2022 @ 8:30 PM
More innovative applications for Black Hole Quencher (BHQ) dyes
In imaging and detection assay development,...
Updated : Wed, March 22, 2023 @ 1:23 PM
Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time interrogating a sample with a new...
Agrigenomics qPCR PCR-based genotyping
Updated : Thu, January 12, 2023 @ 5:10 PM
Rice is the primary staple for more than half the world's population.1 With so many people relying on the crop for...
Oligo synthesis and modifications General science
Updated : Wed, December 14, 2022 @ 4:45 PM
This is the final blog post in a three-part educational series about best practices for in-house oligonucleotide...
Molecular diagnostics Oligo synthesis and modifications
Updated : Tue, January 25, 2022 @ 10:23 PM
This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into...
Oligo synthesis and modifications General science
Updated : Wed, December 14, 2022 @ 4:43 PM
This is the second blog post in a three-part educational series about best practices for in-house oligonucleotide...
Updated : Thu, February 3, 2022 @ 6:10 PM
When results from your qPCR assays aren’t quite what you expected, it can be challenging to understand what went...
Molecular diagnostics qPCR SARS-CoV-2 General science
Updated : Thu, March 31, 2022 @ 3:24 PM
In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges...
Oligo synthesis and modifications General science
Updated : Wed, December 14, 2022 @ 4:43 PM
This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide...
Agrigenomics PCR-based genotyping Nucleic acid extraction
Updated : Tue, September 7, 2021 @ 7:59 PM
Aquaculture breeding programmes adopt genomic technologies, including genotyping, to increase genetic gain for...
Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction
Updated : Thu, August 12, 2021 @ 11:51 PM
Informed plant breeding decisions help drive the field of agrigenomics towards ever-increasing agricultural...
Agrigenomics Nucleic acid extraction
Updated : Wed, August 4, 2021 @ 9:34 PM
A common mistake when initiating an agrigenomics project is failing to consider specific sample composition before...
Agrigenomics Genomics General science
Updated : Wed, December 14, 2022 @ 1:44 PM
The global demand for fish and fish products continues to increase as consumers focus on health-conscious ways to...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Thu, March 9, 2023 @ 5:37 PM
As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to...
Agrigenomics Genomics NGS-based genotyping
Updated : Fri, November 20, 2020 @ 5:16 PM
In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Thu, February 3, 2022 @ 4:39 PM
Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing...
Updated : Wed, October 7, 2020 @ 4:33 PM
“In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish...
Agrigenomics Genomics PCR-based genotyping
Updated : Fri, September 11, 2020 @ 9:52 PM
Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:45 PM
Following up with the panelists from our recent COVID-19 webinar, Part 3 of 3
In the previous two blog posts in this...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:42 PM
Following up with the panelists from our recent COVID-19 webinar, Part 2 of 3
In the face of a rapidly evolving...
Molecular diagnostics Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:45 PM
Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3
The COVID-19 pandemic has presented...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:44 PM
As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal”...
Agrigenomics Genomics PCR-based genotyping
Updated : Tue, July 14, 2020 @ 1:30 PM
Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique...
Molecular diagnostics Genomics qPCR SARS-CoV-2
Updated : Fri, December 18, 2020 @ 8:49 PM
It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned...
Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 General science
Updated : Wed, March 22, 2023 @ 1:52 PM
We’re not rejecting you, just your oligo
PCR is arguably one of the most enabling technologies of modern molecular...
Genomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Wed, April 1, 2020 @ 8:12 PM
Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and...
Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2
Updated : Tue, October 6, 2020 @ 6:44 PM
In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with...
Molecular diagnostics Genomics SARS-CoV-2 General science
Updated : Tue, March 21, 2023 @ 3:41 PM
*Since the original publication of this blog, LGC Biosearch Technologies is now the only acceptable commercial supplier...
Molecular diagnostics Genomics SARS-CoV-2
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Genomics PCR-based genotyping NGS-based genotyping
Updated : Mon, January 13, 2020 @ 5:08 PM
Best practice in sample collection for SeqSNP targeted genotyping by sequencing projects
When good goes in, great...
Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping
Updated : Wed, May 1, 2019 @ 3:59 PM
Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the...
Updated : Fri, March 29, 2019 @ 4:39 PM
We've heard it said for years, "TV will rot your brain". But in the case of our three colleagues below, that definitely...
Updated : Wed, January 9, 2019 @ 5:03 PM
Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays
Updated : Mon, September 19, 2022 @ 2:14 PM
While the science of pharmacogenomics has been around for years, its popularity is starting to pick up steam as...
Genomics Nucleic acid extraction
Updated : Thu, June 28, 2018 @ 4:28 PM
Imagine a time capsule the size of a shoebox that holds all the information currently on the internet that can be stored...
Updated : Tue, May 29, 2018 @ 3:47 PM
Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice...
Updated : Mon, April 30, 2018 @ 1:53 PM
To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data...
Updated : Thu, March 29, 2018 @ 4:00 PM
Ask any little girl what they want to be when they grow up and you may hear things like, princess, ballerina, pop star,...
Updated : Tue, January 16, 2018 @ 4:50 PM
Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous...
Agrigenomics Genomics NGS-based genotyping General science
Updated : Mon, September 19, 2022 @ 2:16 PM
With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the...
Agrigenomics Genomics PCR-based genotyping
Updated : Wed, November 22, 2017 @ 1:44 PM
Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global...
Agrigenomics Genomics PCR-based genotyping
Updated : Tue, July 10, 2018 @ 9:08 PM
Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5...
Genomics PCR-based genotyping Disease detection General science
Updated : Mon, September 19, 2022 @ 2:14 PM
3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious...
RNA FISH Genomics General science
Updated : Thu, July 6, 2017 @ 3:22 PM
Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our...
Updated : Mon, September 19, 2022 @ 2:07 PM
LGC's Genomics Division has signed a memorandum of understanding (MOU) with Chinese health management expert...
RNA FISH Disease detection General science
Updated : Mon, March 6, 2017 @ 4:37 PM
New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus spreads...
Genomics PCR-based genotyping General science
Updated : Wed, February 15, 2017 @ 4:23 PM
Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand...
Updated : Mon, September 19, 2022 @ 2:05 PM
The advent of and ongoing improvements to next-generation sequencing technologies is driving the continuing and...
Updated : Mon, January 23, 2017 @ 4:27 PM
Nature versus nurture. It’s a tale as old as time.
When Craig Venter made the comment after the human genome sequence...
Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science
Updated : Wed, January 18, 2017 @ 2:13 PM
Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable...
Updated : Mon, September 19, 2022 @ 2:15 PM
It seems everyone wants to do more with less, and automate the process as well. But this can cause a number of...
RNA FISH Genomics General science
Updated : Mon, September 19, 2022 @ 2:12 PM
It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a...
Updated : Mon, November 28, 2016 @ 11:31 PM
The secret of life. That’s what Francis Crick and James Watson claimed they had discovered back in Cambridge,...
Updated : Mon, November 21, 2016 @ 3:32 PM
In the early 1900s, scientists found that the function of genes was to make proteins, disproving the earlier idea...
Updated : Wed, March 29, 2023 @ 10:51 AM
The strands of DNA in your cells are organized into pieces called chromosomes. Chromosomes are further organized into...
Updated : Mon, September 19, 2022 @ 2:13 PM
Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne, Australia have blamed a default...
Updated : Wed, March 29, 2023 @ 11:04 AM
As the Zika virus outbreak spreads, a wave of international concern has grown, and scientists have scrambled to...
Oligo synthesis and modifications General science
Updated : Wed, March 29, 2023 @ 10:55 AM
Thio C6 Linker (Thiohexyl)
We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide...
Molecular diagnostics Oligo synthesis and modifications qPCR General science
Updated : Wed, December 14, 2022 @ 5:04 PM
OLIGO SYNTHESIS PHOTO GLIMPSE
We’ve recently captured our talented manufacturing teams hard at work building...
Updated : Wed, August 16, 2017 @ 9:15 AM
Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone...
Updated : Tue, September 27, 2022 @ 2:32 PM
Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells...
Oligo synthesis and modifications qPCR General science
Updated : Wed, March 29, 2023 @ 10:54 AM
This week, we continue our Know your oligo mod blog series and we will focus on a very basic, yet extremely versatile...
Updated : Wed, August 16, 2017 @ 9:13 AM
Here we continue our “Imaging Stellaris Assays” blog series. We last left off talking about the most important...
Updated : Tue, March 21, 2023 @ 3:53 PM
The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the...
Updated : Wed, August 16, 2017 @ 9:42 PM
Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of...
Oligo synthesis and modifications General science
Updated : Wed, March 29, 2023 @ 10:38 AM
Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine,...
Oligo synthesis and modifications General science
Updated : Fri, January 13, 2023 @ 11:35 AM
In this instalment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary non-fluorescent...
Updated : Fri, November 13, 2015 @ 9:25 PM
Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are...
Updated : Tue, March 21, 2023 @ 3:37 PM
Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers...
Updated : Fri, November 13, 2015 @ 10:27 PM
This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia,...
Updated : Fri, November 13, 2015 @ 10:40 PM
In the setup of a qPCR experiment, one of the first decisions to make is which detection method to use. This...
Updated : Mon, November 16, 2015 @ 3:55 PM
Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its...
Oligo synthesis and modifications General science
Updated : Wed, March 29, 2023 @ 10:56 AM
This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for...
Updated : Mon, November 16, 2015 @ 5:30 PM
In a webinar linked below, Dr. James Willey describes a two colour fluorometric assay for more robust quantitation...
qPCR PCR-based genotyping General science
Updated : Mon, September 19, 2022 @ 2:12 PM
Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in...
Oligo synthesis and modifications General science
Updated : Wed, March 29, 2023 @ 10:56 AM
The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo...
Updated : Mon, September 19, 2022 @ 2:14 PM
Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or...