New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future
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Considerations for RT-qPCR in molecular point of care testing devices
The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests becoming commonplace in schools, places of work and people’s homes. Antigen POCT has been pivotal in SARS-CoV-2 detection, particularly where reverse transcription PCR (RT-PCR) cannot be delivered in a timely manner. However, the use of antigen tests isn’t always appropriate due to variable sensitivity. RT-PCR – or RT-qPCR if using real-time detection – offers greater sensitivity and specificity. Leveraging this technology in POCT brings lab quality results to the point of need, providing rapid, accurate and actionable results to clinicians.
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Let the application be your guide when deciding between LNA, MGB and BHQplus The many different chemistries available ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, qPCR
This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
More innovative applications for Black Hole Quencher (BHQ) dyes In imaging and detection assay development, innovative ...
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This is the final blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications
This is the second blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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We’re not rejecting you, just your oligo PCR is arguably one of the most enabling technologies of modern molecular ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide modification: the Thio C6 ...
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OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...
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Topics: Molecular Diagnostics, Real-time PCR, Oligo synthesis and modifications
This week, we continue our Know Your Oligo Mod series and we will focus on a very basic, yet extremely versatile ...
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Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine, ...
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In this installment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary quencher chromophores ...
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This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...
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The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...
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Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...
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A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...
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When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR. When the ...
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Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...
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