Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection ...
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Choosing the best qPCR probe chemistry for your assay
There are many different chemistries available for qPCR probes offering scientists a wealth of options during assay development. However, the unique chemistry of each probe type means that you’ll get the best assay performance when you match the probe type to the application.
Read on to find out more about the chemistries in our industry-leading probe portfolio and what makes each of them shine.
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New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
Let the application be your guide when deciding between LNA, MGB and BHQplus The many different chemistries available ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, qPCR
This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the ...
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Topics: Oligo synthesis and modifications, Nucleic acid therapeutics
More innovative applications for Black Hole Quencher (BHQ) dyes In imaging and detection assay development, innovative ...
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This is the final blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications
This is the second blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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We’re not rejecting you, just your oligo PCR is arguably one of the most enabling technologies of modern molecular ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2
Thio C6 Linker (Thiohexyl) We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide ...
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OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...
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Topics: Molecular Diagnostics, Real-time PCR, Oligo synthesis and modifications
This week, we continue our Know your oligo mod blog series and we will focus on a very basic, yet extremely versatile ...
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Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine, ...
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In this instalment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary non-fluorescent ...
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This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...
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The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...
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Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...
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A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...
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When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR? When the ...
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Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...
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