Choosing the best qPCR probe chemistry for your assay

Choosing the best qPCR probe chemistry for your assay

There are many different chemistries available for qPCR probes offering scientists a wealth of options during assay development. However, the unique chemistry of each probe type means that you’ll get the best assay performance when you match the probe type to the application.

Read on to find out more about the chemistries in our industry-leading probe portfolio and what makes each of them shine.

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AMP conference 2022: Developing a 5-minute point-of-care PCR test

Posted on Wed, Jan 11, 2023 @ 08:15 AM

We were delighted to attend the Association for Molecular Pathology (AMP) 2022 annual meeting, held in Phoenix, Arizona ...
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Topics: Molecular Diagnostics, SARS-CoV-2, Disease detection

What’s next for aptamers in diagnostics?

Posted on Thu, Nov 10, 2022 @ 08:17 AM

Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications

How to select an effective nucleic acid isolation method for human diagnostics?

Posted on Tue, Oct 18, 2022 @ 10:19 AM

Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality ...
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Topics: Molecular Diagnostics, Nucleic acid extraction

Choosing the best qPCR probe chemistry for your assay

Posted on Thu, Jul 28, 2022 @ 10:15 AM

Let the application be your guide when deciding between LNA, MGB and BHQplus  The many different chemistries available ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, qPCR

Pivoting to monkeypox diagnostics

Posted on Thu, Jul 07, 2022 @ 05:38 PM

Since 13 May 2022, reports of monkeypox cases began to appear globally in regions not endemic to the monkeypox virus.1 ...
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Topics: Molecular Diagnostics, Disease detection

Optimising automated high-throughput pathogen detection workflows

Posted on Wed, Mar 30, 2022 @ 11:00 AM

While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient ...
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Topics: Molecular Diagnostics, qPCR

Considerations for RT-qPCR in molecular point of care testing devices

Posted on Tue, Mar 01, 2022 @ 03:11 PM

The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests ...
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Topics: Molecular Diagnostics, qPCR

Technical bulletin: Omicron impact on SARS-CoV-2 mutation analysis and investigation

Posted on Thu, Dec 23, 2021 @ 11:45 AM

The emergence of the Omicron lineage has quickly escalated to be a variant of concern by the World Health Organization ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Ensuring our diagnostic assays detect the Omicron variant

Posted on Thu, Dec 09, 2021 @ 04:24 PM

On 22 November 2021, The Network for Genomics Surveillance in South Africa detected a new SARS-CoV-2 variant, named the ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Extensions to the IVDR - what diagnostics manufacturers and suppliers need to know

Posted on Thu, Dec 02, 2021 @ 05:25 PM

We're excited to announce that the proposal to extend certain key provisions of the In Vitro Diagnostic Regulation ...
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Topics: Molecular Diagnostics

Streamlining diagnostic workflows for common respiratory diseases, such as SARS-CoV-2, influenza and RSV

Posted on Tue, Nov 30, 2021 @ 04:29 PM

A fourth wave of COVID-19 has already emerged in many countries and a newly classified variant of concern, Omicron ...
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Topics: Molecular Diagnostics, SARS-CoV-2, Disease detection

Innovative applications for Black Hole Quencher dyes

Posted on Tue, Nov 16, 2021 @ 04:14 PM

This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications

Technical bulletin: SARS-CoV-2 mutation analysis and investigation

Posted on Thu, Oct 14, 2021 @ 05:01 PM

SARS-CoV-2 mutations and associated new variants are being reported regularly in the media and scientific literature. ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Can COVID-19 testing be made more sustainable during prolonged uncertainty?

Posted on Mon, Sep 27, 2021 @ 02:36 PM

In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges ...
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Topics: Molecular Diagnostics, qPCR, SARS-CoV-2

The surprising global impacts of Europe's In Vitro Diagnostic Regulation (IVDR)

Posted on Thu, Sep 16, 2021 @ 12:15 PM

A shortcut to understanding how to prepare for IVDR In today’s global environment, even small regulatory changes in one ...
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Topics: Molecular Diagnostics

Tips for early-stage MDx companies launching new tests during COVID-19 times

Posted on Thu, Sep 02, 2021 @ 02:00 PM

The COVID-19 pandemic brought tremendous change to the molecular diagnostics (MDx) industry, delivering opportunities ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Genomic surveillance: 3 techniques to detect and characterise SARS-CoV-2 variants

Posted on Wed, May 19, 2021 @ 11:34 AM

As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

Posted on Tue, May 04, 2021 @ 11:03 AM

Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Building resilience into SARS-CoV-2 testing workflows: considerations for choosing an RNA isolation method

Posted on Wed, Oct 21, 2020 @ 11:00 AM

Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Pressing COVID-19 testing issues of today and the near future

Posted on Wed, Aug 26, 2020 @ 09:57 AM

Following up with the panelists from our recent COVID-19 webinar, Part 3 of 3 In the previous two blog posts in this ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Sensitivity and accuracy in COVID-19 testing

Posted on Wed, Aug 19, 2020 @ 09:56 AM

Following up with the panelists from our recent COVID-19 webinar, Part 2 of 3 In the face of a rapidly evolving ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Scaling up COVID-19 viral testing

Posted on Wed, Aug 12, 2020 @ 09:47 AM

Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3 The COVID-19 pandemic has presented ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Enabling a rapid response to COVID-19 by Honeywell and LGC, Biosearch Technologies

Posted on Wed, Jul 29, 2020 @ 02:40 PM

As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal” ...
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Topics: Molecular Diagnostics, Genomics, qPCR, SARS-CoV-2

Robust supply chains and open testing systems: How our AgBio roots meet the FDA's EUA process to enable solutions to the COVID-19 pandemic

Posted on Tue, May 19, 2020 @ 10:18 AM

It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned to ...
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Topics: Molecular Diagnostics, Genomics, qPCR, SARS-CoV-2

Behind the scenes: How our oligo synthesis team contributes to the reliability of your assays

Posted on Thu, Apr 30, 2020 @ 04:13 PM

We’re not rejecting you, just your oligo PCR is arguably one of the most enabling technologies of modern molecular ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2

When you don’t need an EUA for SARS-CoV-2 testing

Posted on Fri, Apr 10, 2020 @ 05:00 PM

On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they will ...
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Topics: Molecular Diagnostics, SARS-CoV-2

Addressing COVID-19 together: LGC, Biosearch Technologies and Shanghai Liferiver Biotechnology Co., Ltd.

Posted on Tue, Mar 31, 2020 @ 12:13 PM

In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...
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Topics: Molecular Diagnostics, Oligo synthesis and modifications, Genomics, SARS-CoV-2

What diagnostic test makers and CLIA labs in the US need to know about Emergency Use Authorization (EUA)

Posted on Tue, Mar 24, 2020 @ 01:58 PM

*Since the original publication of this blog, LGC Biosearch Technologies is now the only acceptable commercial supplier ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Coronavirus outbreak: Collaboration to meet the challenge

Posted on Mon, Mar 16, 2020 @ 02:30 PM

Coronavirus, or COVID-19, is an infectious virus that is spreading rapidly around the world and the World Health ...
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Topics: Molecular Diagnostics, Genomics, SARS-CoV-2

Molecular diagnostics: how can NGS live up to its promises?

Posted on Wed, Jan 29, 2020 @ 11:37 AM

The development of new genomic sequencing techniques and bioinformatics analysis in the last decade has led to massive ...
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Topics: Molecular Diagnostics, Next Generation Sequencing (NGS)

Photoblog: Behind the scenes of oligo synthesis

Posted on Wed, May 18, 2016 @ 05:00 PM

OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...
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Topics: Molecular Diagnostics, Real-time PCR, Oligo synthesis and modifications

RT-qPCR Molecular Diagnostics Assist Workers at the Forefront of Ebola Outbreak.

Posted on Thu, Sep 25, 2014 @ 01:30 PM

The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This ...
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Topics: Molecular Diagnostics, Real-time PCR

qPCR Probes at work: Innovative CLIA test for NSCLC staging

Posted on Tue, Mar 06, 2012 @ 01:00 PM

Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently ...
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Topics: Molecular Diagnostics, Real-time PCR

Visit Biosearch at IVD Technology's Virtual Conference and Tradeshow

Posted on Thu, Sep 23, 2010 @ 04:32 PM

Biosearch Technologies is proud to sponsor the first IVD Technology Virtual Conference and Tradeshow. This free online ...
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Topics: Molecular Diagnostics

PilotDx Oligos: En Route to IVD

Posted on Thu, Jul 22, 2010 @ 10:07 AM

It can be difficult to transition a product from research to commercialization. It’s simply not feasible to conduct ...
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Topics: Molecular Diagnostics

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LGC, Biosearch Technologies is the complete Genomics portfolio from LGC. Providing genomic analysis tools, instrumentation and services to the genomic scientific discovery sector worldwide, with focus on across ag bio, pharma and molecular diagnostics. Visit our home page to view our products and services.

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