In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted selection (MAS) often miss the contributions of a large proportion of the genetic variants or small effects from small loci, which require additional breeding cycles and selections to identify the best lines to take forward. Traditional genotyping data from PCR and microsatellites or single sequence repeats (SSRs) doesn’t provide the details of variation at the sequence level while the fixed nature of arrays prevents them from being adapted to varying accessions, populations and breeding strategies.
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Best practices for implementing targeted genotyping by sequencing
Posted on Wed, Dec 02, 2020 @ 08:53 AM
Topics: Genomics, AgBio, Genomic Selection, Marker Assisted Selection, Targeted Genotyping, Targeted Genotyping by Sequencing
New NGS service lab now open in Middleton, WI for expanded global support
Posted on Wed, Apr 01, 2020 @ 09:27 AM
Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and employs just over 75 people. Lucigen specialises in enzymes, competent cells, and cloning systems to support applications in diagnostics, drug discovery, synthetic biology and gene editing, and now as a part of the Biosearch Technologies portfolio, is expanding next generation sequencing (NGS) services in support of our agricultural biotechnology customers.
Read MoreTopics: Genomics, Targeted Genotyping, Next Generation Sequencing (NGS)
Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the global value of agricultural output.1 This makes the livestock sector one of the fastest growing parts of the agricultural economy, with opportunities for agricultural development, poverty reduction and food security gains.
Read MoreTopics: Agrigenomics, Genomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Arrays, Genomic Library, Targeted Genotyping by Sequencing
Agrigenomics: how can NGS contribute to global food security?
Posted on Wed, Mar 06, 2019 @ 08:33 AM
“Experience of artificial fertilisation, such as is effected with ornamental plants in order to obtain new variations in colour, has led to the experiments which will here be discussed. The striking regularity with which the same hybrid forms always reappeared whenever fertilization took place between the same species induced further experiments to be undertaken.”1
Read MoreTopics: Agrigenomics, Genomics, Sequencing, KASP, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Crop Breeding
How targeted GBS-driven genomic selection can help you get to market faster
Posted on Wed, Jan 16, 2019 @ 11:22 AM
Plant and animal breeding programs often take generations to improve quality and yield but using a genotyping protocol with targeted sequencing can bring you genetic gains faster. Could your plant- or animal breeding program use a boost?
Read MoreTopics: Genomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Animal Breeding, Genomic Library
Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays
Read MoreTopics: Genomics, Sequencing, Targeted Genotyping
Our hungry planet: new tools in agrigenomics are key to food security
Posted on Tue, Dec 11, 2018 @ 08:32 AM
Food security is a major global threat and traditional methods of plant and animal breeding will not be sufficient to increase production to the level needed to sustain the growing world population. Modern genomics-driven breeding, through analysis based on technologies such as next generation sequencing (NGS) and arrays, is revolutionizing agriculture and making genomic selection a viable approach throughout the industry. In this three series blog post find out how technology is changing global food security and what the newest tools bring to the table.
Read MoreTopics: Agrigenomics, Genomic Selection, Targeted Genotyping, Next Generation Sequencing (NGS), Genotyping by Sequencing (GBS), Microarrays, Arrays