The BiosearchTech Blog

When you don’t need an EUA for SARS-CoV-2 testing

On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they will be holding to answer technical questions about developing, validating, and implementing…

Digital PCR – improving reproducible molecular methods in the clinic

Posted on Thu, Apr 06, 2017 @ 08:40 AM

A recent study coordinated by LGC and published in the journal Analytical Chemistry, has demonstrated the potential of ...

Topics: Real-time PCR

qPCR-based Molecular Diagnostics at the Forefront of Zika Surveillance

Posted on Tue, Aug 23, 2016 @ 02:00 PM

As the Zika virus outbreak spreads, a wave of international concern has grown, and scientists have scrambled to ...

Topics: Real-time PCR

Photoblog: Behind the scenes of oligo synthesis

Posted on Wed, May 18, 2016 @ 03:00 PM

OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...

Topics: Molecular Diagnostics, Real-time PCR, Custom Oligos

Nova is the new black

Posted on Thu, Apr 14, 2016 @ 02:00 PM

LGC Biosearch Technologies has developed a new qPCR probe format powered by Black Hole Quencher® technology known as ...

Topics: Real-time PCR

Introducing BHQnova Probes for qPCR - Join the Early Access Program

Posted on Mon, Feb 29, 2016 @ 02:00 PM

LGC Biosearch Technologies is announcing the upcoming release of a new qPCR probe format known as BHQnova™ probes. This ...

Topics: Real-time PCR

Know Your Oligo Mod: 3' Spacer C3

Posted on Thu, Oct 15, 2015 @ 02:15 PM

This week, we continue our Know Your Oligo Mod series and we will focus on a very basic, yet extremely versatile ...

Topics: Real-time PCR, Oligo Modifications

And the Consensus (Sequence) is...

Posted on Thu, Jun 11, 2015 @ 02:31 PM

Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...

Topics: Real-time PCR, RNA FISH

MIQE Goes Digital with Open Access qPCR Guide

Posted on Thu, May 21, 2015 @ 02:00 PM

Since its inception, qPCR has been recognized as a powerful molecular method. However, the application of this ...

Topics: Real-time PCR

Molecular Methods Research Finds a New Home

Posted on Thu, Apr 30, 2015 @ 02:00 PM

The need for improved diligence in research reporting has been echoed in numerous publications which cast doubt on the ...

Topics: Real-time PCR

How Much is Your qPCR Assay Really Costing You?

Posted on Thu, Apr 02, 2015 @ 02:00 PM

In the setup of a qPCR experiment, one of the first decisions to make is which detection method to use. This generally ...

Topics: Real-time PCR

BHQplus Probes Optimize Multiplex Competitive qRT-PCR in Diagnostics

Posted on Thu, Jan 29, 2015 @ 02:00 PM

In a recent webinar, Dr. James Willey describes a two color fluorometric assay for more robust quantitation of nucleic ...

Topics: Real-time PCR

A Successful Duo for Accurate, Speedy, and Economical SNP Genotyping

Posted on Thu, Jan 08, 2015 @ 11:30 AM

Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in forensics, ...

Topics: Real-time PCR, Product Information, SNP Genotyping

Check out our new website qPCR Design Lab @ qPCRdesign.com

Posted on Thu, Oct 23, 2014 @ 02:00 PM

Biosearch Technologies has launched qPCRdesign.com, a new microsite targeted specifically for your quantitative PCR ...

Topics: Real-time PCR, Design Services

Delivering Oligos by Nanomole Units

Posted on Wed, Oct 15, 2014 @ 11:00 AM

Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...

Topics: Real-time PCR, Custom Oligos

RT-qPCR Molecular Diagnostics Assist Workers at the Forefront of Ebola Outbreak.

Posted on Thu, Sep 25, 2014 @ 11:30 AM

The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This ...

Topics: Molecular Diagnostics, Real-time PCR, Biodefense

One Step too Many? Simplify your qPCR Protocol.

Posted on Thu, Feb 27, 2014 @ 10:02 AM

Don’t waste time performing an extra step. Cut back on pipetting and order a ValuMix™ Assay to have your probes and ...

Topics: Real-time PCR, Product Information

30 Years: The Impact of PCR

Posted on Thu, Sep 05, 2013 @ 09:29 AM

Do you remember when the most popular method of DNA amplification involved multiple hybridizations, followed by single ...

Topics: Real-time PCR

RT-qPCR and the Stellaris FISH Method

Posted on Fri, Apr 26, 2013 @ 10:32 AM

A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...

Topics: Real-time PCR, RNA FISH, Referral from the Doctor

qPCR Probes at work: Innovative CLIA test for NSCLC staging

Posted on Tue, Mar 06, 2012 @ 11:00 AM

Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently ...

Topics: Molecular Diagnostics, Real-time PCR

Factors affecting fluorophore performance in qPCR

Posted on Wed, Jan 11, 2012 @ 09:00 AM

A "Referral from the Doctor" Blog Article- In qPCR, fluorescent modified oligos may be either linear or non-linear in ...

Topics: Real-time PCR, Referral from the Doctor

Fluorescence Quenching Mechanisms for Dual-Labeled Probes

Posted on Wed, Jun 29, 2011 @ 07:44 AM

A "Referral from the Doctor" Blog Article- Fluorescent probes are used in biochemical assays to monitor specific events ...

Topics: Real-time PCR, Referral from the Doctor

Multiplexing with Xanthenes

Posted on Wed, Jun 08, 2011 @ 09:13 AM

A "Referral from the Doctor" Blog Article- Quantitative real-time PCR (qPCR) was developed as a means to detect the ...

Topics: Real-time PCR, Referral from the Doctor

qPCR Troubleshooting

Posted on Thu, May 05, 2011 @ 10:23 AM

A "Referral from the Doctor" Blog Article- Quantitative real-time PCR (qPCR) is based upon the fractional cycle number ...

Topics: Real-time PCR, Referral from the Doctor

Biosearch Technologies and Intelligent Medical Devices, Inc. (IMDx) Finalize cGMP Oligo Supply and Licensing Agreements for Molecular Diagnostic Testing (IVD) Products

Posted on Tue, Mar 15, 2011 @ 10:01 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

Between ROX and a Hard Place

Posted on Wed, Nov 10, 2010 @ 09:12 AM

A "Referral from the Doctor" Blog Article- ROX in qPCR Quantitative real-time RT-PCR was developed as a means of ...

Topics: Real-time PCR, Referral from the Doctor

Biosearch Technologies and DuPont Qualicon Finalize Agreements for Food Safety Dx

Posted on Fri, Oct 29, 2010 @ 09:24 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Real-time PCR, Food Safety

Biosearch Technologies and Seegene Finalize Oligonucleotide Supply and BHQ®, CAL Fluor® and Quasar® Licensing Agreements

Posted on Wed, Oct 20, 2010 @ 08:12 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, Real-time PCR

Biosearch Technologies Expands Licensing of QIAGEN Scorpions® Patents

Posted on Thu, Aug 12, 2010 @ 08:41 AM

Biosearch Technologies today announces that it has entered into a new license relationship with QIAGEN (NASDAQ: QIA, ...

Topics: Announcement, Real-time PCR, Product Information

Taq Facts

Posted on Tue, Aug 03, 2010 @ 08:14 AM

A "Referral from the Doctor" Blog Article- When the polymerase chain reaction (PCR) was first described, the Klenow ...

Topics: Real-time PCR, Referral from the Doctor

Pipetting for qPCR

Posted on Wed, Jun 09, 2010 @ 08:41 AM

A "Referral from the Doctor" Blog Article- Research trends in laboratories today increasingly steer towards gene ...

Topics: Real-time PCR, Lab Method, Referral from the Doctor

Easier Online Ordering through RealTimeDesign™ Software

Posted on Wed, May 26, 2010 @ 08:32 AM

RealTimeDesign (RTD TM) Software from Biosearch Technologies is an easy to use, yet powerful assay design application ...

Topics: Real-time PCR, Design Services

Buy One qPCR Probe & Get One FREE

Posted on Fri, May 14, 2010 @ 09:21 AM

Buy one CAL Fluor® or Quasar® -BHQ® Probe and get a FREE ValuProbeTM BHQ Probe* and calibration standard ($190 in ...

Topics: Announcement, Real-time PCR

New Product Line! ValuPanel™ Reagents

Posted on Tue, Apr 06, 2010 @ 08:52 AM

We are pleased to introduce ValuPanel Reagents, a new product line of mission-critical probe and primer sets that ...

Topics: Announcement, Real-time PCR, Product Information, Biodefense

Black Hole Scorpion® Primers - Killer probes for qPCR

Posted on Wed, Mar 24, 2010 @ 08:57 AM

A "Referral from the Doctor" Blog Article- Scorpions®Primers are dual-labeled FRET probes that combine a Molecular ...

Topics: Real-time PCR, Product Information, Referral from the Doctor

Molecular Beacons - Lights in the storm

Posted on Wed, Mar 10, 2010 @ 11:05 AM

A "Referral from the Doctor" Blog Article- Molecular Beacons are a special type of dual-labeled oligonucleotide probe. ...

Topics: Real-time PCR, Referral from the Doctor

Dual-labeled BHQ probes - Performance to “dye” for

Posted on Wed, Feb 24, 2010 @ 10:20 AM

A "Referral from the Doctor" Blog Article- A BHQ® probe is a dual-labeled oligonucleotide covalently labeled with a ...

Topics: Real-time PCR, Referral from the Doctor

This Year's MVP (Most Valuable Practice): Touchdown PCR

Posted on Thu, Feb 04, 2010 @ 10:39 AM

A "Referral from the Doctor" Blog Article- The aim of the Polymerase Chain Reaction (PCR) method is to amplify or ...

Topics: Real-time PCR, Referral from the Doctor

The Grand Ballet: Wine and Biotechnology

Posted on Wed, Jan 27, 2010 @ 11:15 AM

At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS laboratories (ETS) scientist Rich DeScenzo ...

Topics: Real-time PCR

An Alternative to DNAse I heat inactivation: LiCl precipitation

Posted on Wed, Jan 13, 2010 @ 10:04 AM

A "Referral from the Doctor" Blog Article- Genomic DNA contamination has been a hot topic for qPCR researchers since ...

Topics: Real-time PCR, Referral from the Doctor

A Quick Jump Start to Multiplexing qPCR

Posted on Wed, Jan 06, 2010 @ 10:01 AM

By now, you've no doubt read about the reductions in error, cost and time that can be achieved by multiplexing real ...

Topics: Real-time PCR, Design Services

Slope Efficiency Equals Manageable and Corrected PCR

Posted on Wed, Dec 09, 2009 @ 12:01 PM

A "Referral from the Doctor" Blog Article- ε = m.c.2 (shall I explain? slope efficiency equals manageable and ...

Topics: Real-time PCR, Referral from the Doctor

On the Set of "Making of the Swine Flu Test Kit - Inside Biosearch Technologies"

Posted on Thu, Nov 19, 2009 @ 08:29 AM

Biosearch Technologies recently launched a video, Making of the Swine Flu Test Kit - Inside Biosearch Technologies, ...

Topics: Molecular Diagnostics, Real-time PCR, Biodefense

Bringing Back a Champion: Competitive Quantitative Real-time RT-PCR

Posted on Wed, Nov 18, 2009 @ 08:08 AM

A "Referral from the Doctor" Blog Article- Competitive qRT-PCR has become a lost art. Early titans of probe-based PCR ...

Topics: Real-time PCR, Referral from the Doctor

BIOSEARCH TECHNOLOGIES TAKES LICENSE TO CDC H1N1 SIGNATURES AND INFLUENZA A SUB-TYPING PATENT

Posted on Wed, Nov 04, 2009 @ 07:47 AM

Biosearch Technologies announced today that the company has licensed from the CDC the novel H1N1 Influenza signatures ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR, Biodefense

Micronics Acquires License to Biosearch Technologies’ Nucleic Acid Assay Chemistries

Posted on Wed, Oct 28, 2009 @ 01:16 PM

Micronics, Inc., a leading developer of point-of-care molecular diagnostic products, announced today that it has ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

The New Favorite Reference Gene: 36B4, a.k.a. RPLP0

Posted on Wed, Oct 14, 2009 @ 08:06 AM

A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...

Topics: Real-time PCR, Custom Oligos, Referral from the Doctor

DoD Issues SBIR Grants to Biosearch Technologies

Posted on Thu, Oct 08, 2009 @ 08:13 AM

Biosearch Technologies has been selected for two Small Business Innovative Research (SBIR) grants from the Department ...

Topics: Announcement, Molecular Diagnostics, Real-time PCR

What Genes are Hot, What Genes are Not

Posted on Wed, Oct 07, 2009 @ 02:41 PM

A "Referral from the Doctor" Blog Article- Top 10 Reference Genes for probe-based Real-time PCR in 2009: • Acidic ...

Topics: Real-time PCR, Referral from the Doctor

Labeling Oligos with Internal BHQ Dyes

Posted on Tue, Sep 29, 2009 @ 08:16 AM

When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR. When the ...

Topics: Real-time PCR, Product Information, Custom Oligos

Salt-Free Primer Pair Option Now Available

Posted on Tue, Sep 22, 2009 @ 08:08 AM

Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...

Topics: Real-time PCR, Product Information, Custom Oligos

Biosearch Technologies is adding more COLOR to qPCR

Posted on Mon, Sep 21, 2009 @ 02:07 PM

Since its introduction in 2005, the ValuProbe BHQ Probe has become Biosearch Technologies' most popular product sold to ...

Topics: Announcement, Real-time PCR, Product Information

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