The BiosearchTech Blog

How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible for the COVID-19 pandemic from clinical samples in Wuhan, China. Four variants, UK (B1.1.7), B1.1.7 +E484K, South African (B1.351, 501v2) and Brazilian (B1.1.28, P1), are of particular concern. The United States Center for Disease Control and Prevention (CDC) warns that these variants have the potential to...

The BiosearchTech Blog

Shining a light on gene expression and regulation one cell at a time

Posted on Thu, Apr 19, 2018 @ 10:51 AM

To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data ...

Topics: RNA FISH, Genomics, Stellaris

A Stellar-is Year in the Making

Posted on Wed, Dec 07, 2016 @ 08:05 AM

It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a ...

Topics: Product Information, RNA FISH, Genomics, Stellaris

Imaging Stellaris Assays Part III: Creating Professional, Publication-ready Images

Posted on Thu, Mar 10, 2016 @ 02:00 PM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone over ...

Topics: RNA FISH

Welcome to the Stellaris® Citation Center

Posted on Thu, Feb 11, 2016 @ 02:16 PM

We have recently released a Stellaris® RNA FISH Citation Center to make it easy to find publications related to your ...

Topics: RNA FISH

Designing Stellaris RNA FISH Probes Part I: Increasing Probe Count

Posted on Thu, Jan 14, 2016 @ 02:00 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells and ...

Topics: RNA FISH

Imaging Stellaris Assays Part II: How to Acquire Stunning Images

Posted on Thu, Sep 24, 2015 @ 02:30 PM

Here we continue our “Imaging Stellaris Assays” blog series. We last left off talking about the most important ...

Topics: RNA FISH

Runaway RNA Stays Put

Posted on Thu, Sep 17, 2015 @ 02:00 PM

The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the ...

Topics: RNA FISH

Imaging Stellaris Assays Part I: Get to Know Your Microscope

Posted on Thu, Aug 27, 2015 @ 05:00 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of ...

Topics: RNA FISH

And the Consensus (Sequence) is...

Posted on Thu, Jun 11, 2015 @ 02:31 PM

Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are ...

Topics: Real-time PCR, RNA FISH

Research Highlight: Bringing Vision Research into Focus

Posted on Thu, May 28, 2015 @ 02:14 PM

Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers ...

Topics: RNA FISH

FISH-ing for Fusions: A unique approach to fusion gene mRNA & pre-mRNA detection in cancer

Posted on Fri, May 15, 2015 @ 01:00 PM

This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia, PA ...

Topics: RNA FISH

Research Highlight: Localizing long non-coding RNA (lncRNA)

Posted on Thu, Mar 12, 2015 @ 02:00 PM

A recent paper published in Molecular Cell by Dimitrova et al. from the lab of Dr. Tyler Jacks at MIT, used Stellaris® ...

Topics: RNA FISH

The 4Cs of Stellaris® RNA FISH Buffers

Posted on Thu, Feb 26, 2015 @ 02:00 PM

Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its ...

Topics: RNA FISH

Unraveling the Neural Web: Stellaris® RNA FISH for Neuroscience Research

Posted on Thu, Nov 13, 2014 @ 03:45 PM

Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or mixed ...

Topics: RNA FISH, Lab Method

Five Ways Controls Can Demystify Your Stellaris® RNA FISH Experiment

Posted on Tue, Nov 04, 2014 @ 02:13 PM

Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time interrogating a sample with a new ...

Topics: RNA FISH, Lab Method

Biosearch Technologies Executes Exclusive License for turboFISH™

Posted on Mon, Oct 07, 2013 @ 07:29 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Biosearch Technologies Acquires Majority Stake in LightSpeed Genomics

Posted on Wed, Sep 25, 2013 @ 07:25 AM

Biosearch has acquired a majority stake in LightSpeed Genomics, Inc. (LSG), a Santa Clara, California-based company ...

Topics: Announcement, RNA FISH

RT-qPCR and the Stellaris FISH Method

Posted on Fri, Apr 26, 2013 @ 10:32 AM

A "Referral from the Doctor" Blog Article- Quantitative reverse transcription polymerase chain reaction (RT-qPCR) is a ...

Topics: Real-time PCR, RNA FISH, Referral from the Doctor

Stellaris® Foundation Genes: GAPDH

Posted on Thu, Apr 11, 2013 @ 09:30 AM

Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA were among the first designed at ...

Topics: RNA FISH

Biosearch Technologies, UMDNJ Stellaris® Probe Alliance - NextGen Gene Expression™, SNP FISH™, and iceFISH™ in Research and Clinical Applications

Posted on Mon, Mar 18, 2013 @ 08:43 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Biosearch Technologies Launches Catalogued Stellaris™ RNA FISH Assays

Posted on Mon, Jun 18, 2012 @ 08:08 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Single molecule viral RNA analysis using Stellaris™ FISH technology

Posted on Wed, May 30, 2012 @ 01:00 PM

Image courtesy of: http://www.cdc.gov/h1n1flu/images.htm A cooperative effort between researchers at Mount Sinai ...

Topics: Biodefense, RNA FISH

Biosearch Technologies Launches Improved RNA FISH Design Software

Posted on Mon, Mar 19, 2012 @ 07:54 AM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly ...

Topics: Announcement, RNA FISH

Stellaris FISH Workshop at the AMP 2011

Posted on Tue, Nov 15, 2011 @ 01:53 PM

Join us at AMP 2011 on November 16th for a live demonstration of the Stellaris technology at the Gaylord Texan Resort ...

Topics: RNA FISH, Lab Method

Blogging about Stellaris™ RNA FISH at Singlemoleculefish.com

Posted on Mon, Oct 24, 2011 @ 12:24 PM

Biosearch Technologies is starting a new sister blog at singlemoleculefish.com where all articles will focus on topics ...

Topics: Announcement, RNA FISH

Biosearch Technologies Announces Release of Custom Stellaris™ FISH Probes

Posted on Mon, Sep 12, 2011 @ 04:59 AM

Stellaris FISH advances research in cancer, developmental biology and pathology by resolving in situ messenger RNA into ...

Topics: RNA FISH

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How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?