How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible for the COVID-19 pandemic from clinical samples in Wuhan, China. Four variants, UK (B1.1.7), B1.1.7 +E484K, South African (B1.351, 501v2) and Brazilian (B1.1.28, P1), are of particular concern. The United States Center for Disease Control and Prevention (CDC) warns that these variants have the potential to...

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Know Your Oligo Mod: Thio C6 Linker

Posted on Thu, Jul 14, 2016 @ 02:00 PM

We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide modification: the Thio C6 ...
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Topics: Oligo Modifications

Know Your Oligo Mod: 3' Spacer C3

Posted on Thu, Oct 15, 2015 @ 02:15 PM

This week, we continue our Know Your Oligo Mod series and we will focus on a very basic, yet extremely versatile ...
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Topics: Real-time PCR, Oligo Modifications

Know Your Oligo Mod: Phosphorothioate Bonds

Posted on Thu, Feb 12, 2015 @ 02:00 PM

This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...
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Topics: Custom Oligos, Oligo Modifications

Know Your Oligo Mod: Methylene Blue

Posted on Tue, Dec 09, 2014 @ 02:02 PM

The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...
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Topics: Custom Oligos, Oligo Modifications

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