How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

How do SARS-CoV-2 variants affect PCR assays for COVID-19 testing?

Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible for the COVID-19 pandemic from clinical samples in Wuhan, China. Four variants, UK (B1.1.7), B1.1.7 +E484K, South African (B1.351, 501v2) and Brazilian (B1.1.28, P1), are of particular concern. The United States Center for Disease Control and Prevention (CDC) warns that these variants have the potential to...

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Oligonucleotide synthesis basics: Introduction to phosphoramidite chemistry

Posted on Tue, Sep 14, 2021 @ 12:00 PM

This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide ...
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Topics: Oligo synthesis, Nucleic acid chemistry

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