The BiosearchTech Blog

Scaling up COVID-19 viral testing

Posted on Wed, Aug 12, 2020 @ 07:47 AM

Following up with the panelists from our recent COVID-19 webinar, Part 1 of 3

The COVID-19 pandemic has presented testing labs around the world with a number of new challenges, and the community is still working out the best ways to meet the incredible testing need. To help labs continue to refine and improve their SARS-CoV-2 testing processes and workflows, LGC, Biosearch Technologies recently held an information-rich webinar, 'How to establish COVID-19 diagnostics and keep up with demand', with a panel of experts from both industry and academia. Here we follow-up with two of the panelists, Eric Chow, PhD, and Kathleen Campau, PhD, with additional questions from the audience on scaling up. 

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Topics: Genomics, Coronavirus

Enabling a rapid response to COVID-19 by Honeywell and LGC, Biosearch Technologies

Posted on Wed, Jul 29, 2020 @ 12:40 PM

As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal” without a vaccine for COVID-19 or effective treatments in place, prudent testing measures need to be taken to suppress new infections. It is critical to test more people rapidly to identify who is infected, track them to avoid the disease from spreading and tracing with whom they have been in contact. Reverse transcription PCR (RT-PCR) testing method currently represents the majority of COVID-19 molecular diagnostics that helps identify individuals who are infected at the time of the test.

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Topics: Genomics, qPCR, Coronavirus

Establishment of KASP marker library for genetic diversity analysis in Brassica rapa  crops

Posted on Tue, Jul 14, 2020 @ 08:17 AM

Brassica  rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique opportunity for investigating plant genome evolution. In 2018, the Food and Agricultural Organization reported a global production of cabbages and other brassicas to be more than 103 million tonnes.1 Disease and environmental stress can reduce crop yield and quality, so plant breeders are using genome-wide molecular markers like SNPs to make a background selection and identify target genes involved in high nutritional quality, disease resistance and yield in order to speed up the breeding process in Brassica rapa crops. 

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Topics: Agrigenomics, Genomics, KASP

Robust supply chains and open testing systems: How our AgBio roots enable solutions to the COVID-19 pandemic

Posted on Tue, May 19, 2020 @ 08:18 AM

It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned to help COVID-19 testing labs overcome bottlenecks and rapidly scale-up testing. However, when you look at the problems testing labs are facing, it becomes clear that LGC, Biosearch Technologies has all the right tools for a rapid and robust pandemic response, even with the need to validate our Research Use Only (RUO) products for diagnostic testing. Today’s significantly altered conditions require new approaches and new solutions.

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Topics: Genomics, qPCR, Coronavirus

Behind the scenes: How our oligo synthesis team contributes to the reliability of your assays

Posted on Thu, Apr 30, 2020 @ 02:13 PM

We’re not rejecting you, just your oligo

PCR is arguably one of the most enabling technologies of modern molecular biology, with a sensitivity that can detect incredibly small amounts of DNA. However, the sensitivity of the method is also one of the biggest challenges—when you can detect just a few molecules of DNA, inadvertent contamination can give you misleading data. Issues with contamination are especially critical in qPCR reactions for molecular diagnostics testing, such as for SARS-CoV-2 detection, where any contaminating template DNA, even if it’s just long fragments, can generate false positive results.

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Topics: Genomics, Coronavirus, Oligo synthesis

Expanded SeqSNP support with new NGS lab in Middleton, WI

Posted on Tue, Apr 14, 2020 @ 09:15 AM

LGC, Biosearch Technologies is excited to announce the expansion of SeqSNP targeted genotyping by sequencing (GBS) services in North America. Advancing AgBio projects from our Middleton, Wisconsin, USA, location, these services provide an all-inclusive, cost-effective targeted GBS solution that requires no setup costs or upfront sample number commitment.

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Topics: Agrigenomics, Genomics, GBS, SeqSNP, Genotyping by Sequencing (GBS), Targeted Genotyping by Sequencing

New NGS service lab now open in Middleton, WI for expanded global support

Posted on Wed, Apr 01, 2020 @ 09:27 AM

Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and employs just over 75 people. Lucigen specialises in enzymes, competent cells, and cloning systems to support applications in diagnostics, drug discovery, synthetic biology and gene editing, and now as a part of the Biosearch Technologies portfolio, is expanding next generation sequencing (NGS) services in support of our agricultural biotechnology customers.

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Topics: Genomics, Targeted Genotyping, Next Generation Sequencing (NGS)

Addressing COVID-19 together: LGC, Biosearch Technologies and Shanghai Liferiver Biotechnology Co., Ltd.

Posted on Tue, Mar 31, 2020 @ 10:13 AM

In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with the World Health Organization (WHO) reporting 113,702 confirmed cases of COVID-19 as of March 10, 2020, with 80,924 of those cases in China and the remaining 32,778 cases spread across 109 countries1.

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Topics: Custom Oligos, Genomics, Coronavirus

What diagnostic test makers and CLIA labs in the US need to know about Emergency Use Authorization (EUA)

Posted on Tue, Mar 24, 2020 @ 11:58 AM

As the COVID-19 pandemic challenges society with the largest public health crisis of modern times, testing is a crucial part of the response. In the United States (U.S.), getting tests into the community has been challenging, in part due to the need to obtain an Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA); however, in recent weeks, the US government has been doing its best to partner with private industry where the FDA has been fast-tracking more EUAs in effort to making testing more widely available across the country.

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Topics: Genomics, Coronavirus

Coronavirus outbreak: Collaboration to meet the challenge

Posted on Mon, Mar 16, 2020 @ 12:30 PM

Petaluma video clip for coronavirus landing page 1-1

Coronavirus, or COVID-19, is an infectious virus that is spreading rapidly around the world and the World Health Organisation (WHO) declared the outbreak a global health emergency within weeks of its identification. As of 11 March, WHO announced that the Coronavirus outbreak has become a global pandemic.

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Topics: Genomics, Coronavirus

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About Biosearch Technologies

As the inventor of the BHQ dyes, Biosearch Technologies synthesizes sophisticated oligos for real time qPCR, molecular diagnostics, and more!  Visit our home page to view our products and services.

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