The BiosearchTech Blog

Considerations for RT-qPCR in molecular point of care testing devices

The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests becoming commonplace in schools, places of work and people’s homes. Antigen POCT has been pivotal in SARS-CoV-2 detection, particularly where reverse transcription PCR (RT-PCR) cannot be delivered in a timely manner. However, the use of antigen tests isn’t always appropriate due to variable sensitivity. RT-PCR – or RT-qPCR if using real-time detection – offers greater sensitivity and specificity. Leveraging this technology in POCT brings lab quality results to the point of need, providing rapid, accurate and actionable results to clinicians.

Addressing COVID-19 together: LGC, Biosearch Technologies and Shanghai Liferiver Biotechnology Co., Ltd.

Posted on Tue, Mar 31, 2020 @ 10:13 AM

In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with ...

Topics: Molecular Diagnostics, Custom Oligos, Genomics, Coronavirus

Photoblog: Behind the scenes of oligo synthesis

Posted on Wed, May 18, 2016 @ 03:00 PM

OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building oligos. ...

Topics: Molecular Diagnostics, Real-time PCR, Custom Oligos

The AGCT’s of DNA Synthesis

Posted on Tue, Aug 11, 2015 @ 02:00 PM

Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine, ...

Topics: Custom Oligos, Synthesis Reagents

Know Your Oligo Mod: BHQ® (Black Hole Quencher®) Dyes

Posted on Thu, Jul 23, 2015 @ 02:00 PM

In this installment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary quencher chromophores ...

Topics: Custom Oligos

Celebrate World DNA Day 2015

Posted on Tue, Apr 21, 2015 @ 03:02 PM

This Saturday, April 25, 2015, will commemorate the 12th World DNA Day - A holiday which is not well known to most ...

Topics: Custom Oligos

Know Your Oligo Mod: Phosphorothioate Bonds

Posted on Thu, Feb 12, 2015 @ 02:00 PM

This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for ...

Topics: Custom Oligos, Oligo Modifications

Know Your Oligo Mod: Methylene Blue

Posted on Tue, Dec 09, 2014 @ 02:02 PM

The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo ...

Topics: Custom Oligos, Oligo Modifications

Delivering Oligos by Nanomole Units

Posted on Wed, Oct 15, 2014 @ 11:00 AM

Different oligonucleotide manufacturers deliver probes and primers in a variety of different measured units including ...

Topics: Real-time PCR, Custom Oligos

The New Favorite Reference Gene: 36B4, a.k.a. RPLP0

Posted on Wed, Oct 14, 2009 @ 08:06 AM

A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two subunits, one small (40S) and one large ...

Topics: Real-time PCR, Custom Oligos, Referral from the Doctor

FDA Awards Biosearch Technologies $3.4 MM Contract

Posted on Mon, Oct 05, 2009 @ 07:48 AM

The FDA has awarded Biosearch Technologies a five year contract for the development of multiplexed, fluorescent ...

Topics: Molecular Diagnostics, Custom Oligos, Food Safety, Biodefense

Labeling Oligos with Internal BHQ Dyes

Posted on Tue, Sep 29, 2009 @ 08:16 AM

When to use an internal Black Hole Quencher (BHQ) label in a fluorescence-quenched probe for real-time qPCR. When the ...

Topics: Real-time PCR, Product Information, Custom Oligos

Salt-Free Primer Pair Option Now Available

Posted on Tue, Sep 22, 2009 @ 08:08 AM

Biosearch Technologies will now be offering the option of salt-free primer pairs for purchase with any probe order. A ...

Topics: Real-time PCR, Product Information, Custom Oligos

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Considerations for RT-qPCR in molecular point of care testing devices