The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This epidemic has presented a public health emergency to national and international disease control centers with aid workers tirelessly working to assist affected communities. Ebola is a single-stranded RNA virus that has five known strains, four of which are pathogenic to humans. The current outbreak is a result of the spread of the Zaire ebolavirus (EBOV) strain which previously averaged a 78% mortality rate 1. In a recent update from the World Health Organization, upwards of 2,600 deaths have been reported as result of the viral infection over the last several months 2.
The BiosearchTech Blog
Biosearch Technologies, Inc. (Biosearch) announced today that the company has implemented a rapid response to the current outbreak of Avian Influenza Virus A (H7N9) in China. Biosearch is ready to provide to the scientific community on-demand, rapid synthesis of real-time qPCR probes and primers composing the H7N9 detection panel recently developed and published on 8 April by the World Health Organization (WHO) Collaborating Center for Reference and Research on Influenza in Beijing, China. WHO lists FAM-BHQ® probes as crucial reagents in their protocol named, “Real-time RT-PCR Protocol for the Detection of A(H7N9) Influenza Virus,” which is available for download at:
|Image courtesy of: http://www.cdc.gov/h1n1flu/images.htm|
A cooperative effort between researchers at Mount Sinai School of Medicine in New York and the University of Illinois at Urbana-Champaign demonstrates a novel experimental system for single-molecule sensitivity FISH analysis of individual virus particles.
Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly growing molecular diagnostics industry, today announced that the company has licensed access to the new “pdm” H1N1 signatures from Centers for Disease Control and Prevention (CDC). The new “pdm” panel is optimized to achieve enhanced sensitivity and specificity for H1N1 specimen.
Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly growing molecular diagnostics industry, today announced that the company has been awarded another Phase II Small Business Innovative Research (SBIR) grant from the Department of Defense (DoD).
We are pleased to introduce ValuPanel Reagents, a new product line of mission-critical probe and primer sets that discriminate different strains of pathogens. This product line culminated from our successful collaboration with Centers for Disease Control and Prevention* (CDC) in response to the 2009 H1N1 pandemic. As of now, ValuPanel Reagents are available for both 2009 H1N1 and seasonal Influenza A subtyping.
Biosearch Technologies recently launched a video, Making of the Swine Flu Test Kit - Inside Biosearch Technologies, which had debuted last week at qPCR Symposium 2009 held in Millbrae, California. This video is an accurate re-enactment of Biosearch Technologies' rapid production of the H1N1 (Swine Flu) test kit that was developed by the Centers for Disease Control and Prevention (CDC).
Biosearch Technologies announced today that the company has licensed from the CDC the novel H1N1 Influenza signatures along with the Influenza A sub-typing panel signatures. This licensing agreement with the CDC makes Biosearch Technologies the first oligo manufacturer to have the right to manufacture and sell dual-labeled probes and primers bearing the H1N1 and Influenza A sub-typing signatures.
The FDA has awarded Biosearch Technologies a five year contract for the development of multiplexed, fluorescent bead-based assays to determine bioterror and food safety pathogens. The assay will be conducted on a Luminex® xMap® platform. Throughout the contract, Biosearch will collaborate with scientists at Lawrence Livermore National Laboratories (LLNL) and the Luminex Corporation to develop assays for agents listed by the CDC and USDA. Initial target analytes include Bacillus anthracis, the causative agent of anthrax; Yersinia pestis, the causative agent of the plague; and Francisella tularensis, the causative agent of tularemia.