The BiosearchTech Blog

qPCR-based Molecular Diagnostics at the Forefront of Zika Outbreak

Posted on Tue, Aug 23, 2016 @ 02:00 PM

On February 1, 2016 the World Health Organization (WHO) released a statement of public health concerns over a link between Zika virus and prevalence of microcephaly in the offspring of infected individuals1. Of all the South American countries affected by Zika, Brazil has been hardest hit, with an estimated 1.5 million cases since 20152. Subsequent to the announcement, concern has grown internationally due to the 2016 Olympic games in Rio de Janeiro, Brazil, coinciding with the outbreak. Recently, Centers for Disease Control and Prevention (CDC) issued a historic travel advisory relating to the continental United States due to localized transmission within a region of Miami, FL3,4. Zika cases have also been reported in numerous other US locations, particularly in the territory of Puerto Rico which is under a public health emergency as of August 12, 2016 (see inset map).  CDC advises travelers to take precautions against Zika, and recommends those experiencing symptoms to meet with their physicians5.

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Topics: Real-time PCR

Know Your Oligo Mod: Thio C6 Linker

Posted on Thu, Jul 14, 2016 @ 02:00 PM

We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide modification: the Thio C6 Linker (Thiohexyl) modification.  Figure 1 depicts the reactive handle of a Thio C6 Linker that can be incorporated as either a 5’ modification or a 3’ modification on a custom oligonucleotide. The addition of this custom oligo modification creates a conjugation site with a reactive thiol group.

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Topics: Oligo Modifications

A Complete Ecosystem to Accelerate Breeding Programs [Infographic]

Posted on Tue, Jun 28, 2016 @ 02:00 PM

Modern breeding methods rely on the identification and utilization of molecular markers associated with traits important for plant and animal improvement. Here at LGC, we can bolster your breeding programs with a range of products and services at every step, beginning with research to selection to analysis and production. This infographic summarizes how we can accelerate breeding programs with our cost-effective agrigenomic solutions, whether it be in our labs or yours.

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Topics: Agrigenomics

DNA Technology is now LGC Biosearch Technologies

Posted on Tue, Jun 14, 2016 @ 03:52 PM

For DNA Technology’s existing customers, don’t fret! The online ordering process will remain the same, as will the team assisting you. BHQ® probes, BHQplus® probes, and custom oligos will continue to be offered at the facility in Denmark. This facility is DS/EN ISO 9001:2008 compliant and the products are intended for research and development use. For more consequential assays, GMP manufacturing is also available.

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Topics: Announcement

Photoblog: Behind the scenes of oligo synthesis

Posted on Wed, May 18, 2016 @ 03:00 PM

OLIGO
SYNTHESIS
PHOTO
GLIMPSE

We’ve recently captured our talented manufacturing teams hard at work building oligos. Please enjoy this short visual insight into LGC Biosearch Technologies.

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Topics: Molecular Diagnostics, Real-time PCR, Custom Oligos

Hey! Biosearchtech.com looks different

Posted on Thu, Apr 28, 2016 @ 03:15 PM

We are pleased to announce that LGC Biosearch Technologies’ released a new and improved biosearchtech.com. Thank you to all our web visitors who’ve left feedback over the years. With your suggestions, we developed and consolidated features to better address your needs. Check out these top four improvements:

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Topics: Announcement

Nova is the new black

Posted on Thu, Apr 14, 2016 @ 02:00 PM

LGC Biosearch Technologies has developed a new qPCR probe format powered by Black Hole Quencher® technology known as BHQnova™ probes. This probe format incorporates 5’ fluorophores and 3’ BHQ modifications as seen in standard BHQ® probes, but also introduces a novel Nova quencher placed internally between bases 9 and 10 from the 5’ end of the oligo.

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Topics: Real-time PCR

Learn about the latest developments in technologies for molecular breeding programs

Posted on Thu, Mar 31, 2016 @ 02:00 PM

lgc-symposium-available-online.jpgAt this year’s 24th annual Plant & Animal Genome (PAG) conference, LGC Biosearch Technologies hosted a symposium titled “Latest advancements in genotyping technologies for molecular breeding.” This symposium featured key AgBio opinion leaders and industry professionals to discuss about recent developments within the field of marker assisted selection. The slides and audio from these presentations are now available online for your immediate viewing.  The presenters and their topics are as follows:

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Topics: Announcement

Imaging Stellaris Assays Part III: Creating Professional, Publication-ready Images

Posted on Thu, Mar 10, 2016 @ 02:00 PM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone over microscope hardware and image acquisition.  In this article, we will walk you through some simple downstream image processing that will turn your raw Z-stack images into spectacular-looking, publication-ready images.

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Topics: RNA FISH

Introducing BHQnova Probes for qPCR - Join the Early Access Program

Posted on Mon, Feb 29, 2016 @ 02:00 PM

LGC Biosearch Technologies is announcing the upcoming release of a new qPCR probe format known as BHQnova™ probes. This is an exciting addition to the full range of BHQ qPCR probes including our standard BHQ® hydrolysis probes and our compact BHQplus® probes. The new BHQnova probe is a double-quenched probe, which includes the typical 5’ reporter dye and 3’ BHQ modifications, but also incorporates an additional internal “Nova” quencher. This new probe format allows for longer probe sequences, maintains excellent quenching efficiency, and improves signal-to-noise ratio (S:N) resulting in robust amplification curves. The BHQnova probe format presents yet another option that allows greater design flexibility to tackle almost any qPCR assay design challenge.

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Topics: Real-time PCR

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About Biosearch Technologies

As the inventor of the BHQ dyes, Biosearch Technologies synthesizes sophisticated oligos for real time qPCR, molecular diagnostics, and more!  Visit our home page to view our products and services.

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